Trials Sponsors Conditions Drugs Pricing

Conditions

Amyotrophic Lateral Sclerosis With Dementia

Keywords

AmyotrophicSclerosis

Outcome Measures

Primary Outcomes (1)

Diagnostic certainty 1.ENMG according to El Escorial revised criteria using ENMG alone, MRI alone and ENMG+MRI to define denervation diffusion
number of patients classified as possible, probable or certain according to El Escorial criteria using ENMG alone, IMR alone and ENMR+MRI
1 month

Secondary Outcomes (1)

Define precise topographic and characteristic of muscle involvement in ALS by MRI
1 month

Study Arms (1)

ENMG and muscle analyses on whole body muscles MRI.

EXPERIMENTAL

Diffusion of active and chronic muscle denervation will be assessed on ENMG and whole body muscle MRI. The diagnostic category will be determined by revised El Escorial criteria and Awaji criteria

Diagnostic Test: Whole Body MRI and ENMG

Interventions

Whole Body MRI and ENMGDiagnostic test

Whole body muscle MRI lasting 30 to 45 min without injection of contrast medium an ENMG

ENMG and muscle analyses on whole body muscles MRI.

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years - 99 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Consent form signed by the patient
Patients suspected ALS defined according Awaji Shima criteria (possible, probable, defined)

Sponsors & Collaborators

University Hospital, Toulouse
Otherlead

Study Sites (1)

Pascal CINTAS

Toulouse, 31000, France

RECRUITING

Pascal CINTAS, MD PHDCONTACT0561779440 cintas.p@chu-toulouse.fr

Anne Cecile CovilleCONTACT0534558700

MeSH Terms

Conditions

Amyotrophic Lateral SclerosisSclerosis

Condition Hierarchy (Ancestors)

Spinal Cord DiseasesCentral Nervous System DiseasesNervous System DiseasesMotor Neuron DiseaseNeurodegenerative DiseasesTDP-43 ProteinopathiesNeuromuscular DiseasesProteostasis DeficienciesMetabolic DiseasesNutritional and Metabolic DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

Pascal CINTAS, MD
University Hospital, Toulouse
PRINCIPAL INVESTIGATOR

Central Study Contacts

Pascal CINTAS, MD PHD

CONTACT

05 61 77 94 40 cintas.p@chu-toulouse.fr

Anne Cecile Coville

CONTACT

(05345) 58700

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NA
Masking: NONE
Purpose: DIAGNOSTIC
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

March 26, 2021

First Posted

May 3, 2021

Study Start

June 1, 2021

Actual (reported)

Primary Completion

December 2024

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Magnetic Imaging for Diagnostic of Amyotrophic Lateral Sclerosis

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (1)

ENMG and muscle analyses on whole body muscles MRI.

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (1)

ENMG and muscle analyses on whole body muscles MRI.

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations