The Brain Activation During Different Motor Patterns in Healthy Adults
The Brain Activation During Motor Execution, Motor Imagery, Action Observation, and Mirror Visual Feedback in Healthy Adults
1 other identifier
observational
43
1 country
1
Brief Summary
This study aims to investigate the brain activation during different motor patterns, including motor execution (ME), motor imagery (MI), action observation (AO) and mirror visual feedback (MVF). In addition, the relations between brain activation and motor performance will also be explored. This study includes two parts, which are upper limb and lower limb part. While executing all the tasks, brain activation in primary motor cortex(M1), premotor cortex(PMC), and supplementary motor cortex(SMA) will be monitored by functional near-infrared spectroscopy. One-way ANOVA with repeated measure will be used to detect the differences of brain activation level between each mode. Pearson correlation coefficient will be used to determine the relations of brain activation and motor performance.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started May 2021
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 25, 2021
CompletedStudy Start
First participant enrolled
May 1, 2021
CompletedFirst Posted
Study publicly available on registry
May 3, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 7, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
August 7, 2022
CompletedFebruary 22, 2023
June 1, 2022
1.3 years
April 25, 2021
February 20, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
Brain activities over primary motor cortex
A multichannel wearable fNIRS imaging system (NIRSport2, NIRx Medical Technologies LLC, Glen Head, NY, USA) is used to detect the hemodynamics.
Day 1
Brain activities over premotor cortex
A multichannel wearable fNIRS imaging system (NIRSport2, NIRx Medical Technologies LLC, Glen Head, NY, USA) is used to detect the hemodynamics.
Day 1
Brain activities over supplementary motor area
A multichannel wearable fNIRS imaging system (NIRSport2, NIRx Medical Technologies LLC, Glen Head, NY, USA) is used to detect the hemodynamics.
Day 1
Secondary Outcomes (7)
Motor performance of upper limb -maximum speed
Day 1
Motor performance of upper limb -maximum acceleration
Day 1
Motor performance of upper limb - jerk
Day 1
Motor performance of lower limb - gait speed
Day 1
Motor performance of lower limb - cadence
Day 1
- +2 more secondary outcomes
Eligibility Criteria
The population in this study are heathly adults.
You may qualify if:
- Age between 20 to 30 years.
- Right-handed.
- Ability to walk 30 meters independently without an assistive device.
- No neurogical, cardiopulmonary, or muscle diseases that might interfere with the experiment.
- Mini-Mental State Examination (MMSE) score greater than 24.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
National Taiwan University Hospital
Taipei, Taiwan
Study Officials
- PRINCIPAL INVESTIGATOR
Yanci Liu, PHD
National Taiwan University
Study Design
- Study Type
- observational
- Observational Model
- CASE CROSSOVER
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 25, 2021
First Posted
May 3, 2021
Study Start
May 1, 2021
Primary Completion
August 7, 2022
Study Completion
August 7, 2022
Last Updated
February 22, 2023
Record last verified: 2022-06