NCT04867668

Brief Summary

There is little published data on exposure to and evaluations of large-scale, online tobacco control campaigns. This project addresses the gap. Under 2 specific aims, the investigators will identify the independent effects of varying levels of digital message exposure to promote anti-tobacco attitudes, beliefs, or behaviors among youth and young adults, first through a randomized experiment online, and second through a field-based evaluation. These studies will advance the science of digital health and have wide application to future campaigns.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,800

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2021

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 1, 2021

Completed
19 days until next milestone

Study Start

First participant enrolled

February 20, 2021

Completed
2 months until next milestone

First Posted

Study publicly available on registry

April 30, 2021

Completed
4.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 28, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 28, 2026

Completed
Last Updated

March 10, 2026

Status Verified

March 1, 2026

Enrollment Period

5 years

First QC Date

February 1, 2021

Last Update Submit

March 9, 2026

Conditions

Keywords

VapingSmokingDigital MediaAdvertisingDose-responseRandomized Controlled Trial

Outcome Measures

Primary Outcomes (1)

  • 30-day use of electronic cigarettes (vaping)

    Frequency of vaping during the past 30 days

    Ad Awareness Outcome (Aim 1): By the end of year 1, Vaping & Smoking Outcome (Aim 2): By the end of year 5

Study Arms (2)

Digital intervention

EXPERIMENTAL

Participants will be randomized to receive variable levels of exposure (including no exposure control) of digital anti-vaping and anti-smoking messages. We will evaluate the effects of experimental condition and exposure on outcomes (tobacco product use).

Behavioral: Anti-vaping and anti-smoking digital advertising

Control

NO INTERVENTION

No exposure control condition

Interventions

Delivery of social media based advertising to prevent vaping and smoking among young adults ages 18-24.

Digital intervention

Eligibility Criteria

Age18 Years - 24 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Young adults age 18-24 who are members of the Ipsos/Knowledge Panel

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The George Washington University Milken Institute School of Public Health

Washington D.C., District of Columbia, 20052, United States

Location

Related Publications (2)

  • Evans WD, Ichimiya M, Bingenheimer JB, Cantrell J, D'Esterre AP, Pincus O, Yu LQ, Hair EC. Design and Baseline Evaluation of Social Media Vaping Prevention Trial: Randomized Controlled Trial Study. J Med Internet Res. 2025 Mar 31;27:e72002. doi: 10.2196/72002.

  • Evans WD, Bingenheimer J, Cantrell J, Kreslake J, Tulsiani S, Ichimiya M, D'Esterre AP, Gerard R, Martin M, Hair EC. Effects of a Social Media Intervention on Vaping Intentions: Randomized Dose-Response Experiment. J Med Internet Res. 2024 Mar 12;26:e50741. doi: 10.2196/50741.

MeSH Terms

Conditions

Tobacco UseVapingSmoking

Condition Hierarchy (Ancestors)

Behavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Masking Details
The actual recruitment rate is 2106.
Purpose
PREVENTION
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

February 1, 2021

First Posted

April 30, 2021

Study Start

February 20, 2021

Primary Completion

February 28, 2026

Study Completion

February 28, 2026

Last Updated

March 10, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations