Comparative Study Between CT Arthrography and MRI Arthrography in Detection of Intra-articular Hip Pathology

NCT04863911 | Unknown

• 1 other identifier: CTA vs MRA in hip pathology
• Study Type: observational
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this work is to compare the role of CT hip arthrography to MR arthrography in the detection of intra-articular hip pathology.

Conditions

Hip Disease

Outcome Measures

Primary Outcomes (1)

• Sensitivity

  Sensitivity refers to true positive rate, the percentage of patients with actual illness who was correctly diagnosed in overall patients by each of CT arthrography and MRI arthrography. High sensitivity indicated high correct rate in diagnosis of intra-articular hip pathology.

  1 week

Secondary Outcomes (3)

• Specificity

  1 week

• positive predictive value

  1 week

• Negative predictive value

  1 week

Interventions

combined CT and MRI RADIATION

1 mL of gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) will be diluted with 100 mL of saline; 8 mL of this will be mixed with 7 mL of iodine solution (340 mg/cc) and 3 mL of lidocaine 2% and injected under ultrasonographic guidance. The fixed US-guided technique, the needle will be inserted into the needle guide hole and directed toward the hip joint, targeting the femoral head-neck junction. The volume injected varies from 10 to 20 mL, with a mean of 15 mL. Ideally CT should be performed immediately after the injection and MR should be performed within 90 minutes after the initial injection.

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients of different sex and age groups presenting to the Radiology department with clinical and routine imaging suggestive of intraarticular hip pathology.

You may qualify if:

• consecutive patients presenting with clinical and routine imaging suggestive of intraarticular hip pathology.
• patients must be accept the intraarticular hip injection of contrast.

You may not qualify if:

• Any general contraindication of MRI in some cases as presence of anti-paramagnetic substance as pacemakers aneurysm clips, metallic cochlear implants
• Severely ill patients or those with claustrophobia
• Any general contraindications to radiation in some cases such as pregnancy at first trimester.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (3)

• Llopis E, Fernandez E, Cerezal L. MR and CT arthrography of the hip. Semin Musculoskelet Radiol. 2012 Feb;16(1):42-56. doi: 10.1055/s-0032-1304300. Epub 2012 Mar 23.

  PMID: 22447236 RESULT

• Perdikakis E, Karachalios T, Katonis P, Karantanas A. Comparison of MR-arthrography and MDCT-arthrography for detection of labral and articular cartilage hip pathology. Skeletal Radiol. 2011 Nov;40(11):1441-7. doi: 10.1007/s00256-011-1111-9. Epub 2011 Feb 6.

  PMID: 21298428 RESULT

• Schneider G, Massmann A, Fries P, Kusma M, Dienst M. [Magnetic resonance tomography and arthrography of the hip joint]. Orthopade. 2006 Jan;35(1):22-6, 28-32. doi: 10.1007/s00132-005-0890-x. German.

  PMID: 16322973 RESULT

MeSH Terms

Interventions

Magnetic Resonance Spectroscopy

Intervention Hierarchy (Ancestors)

Spectrum Analysis; Chemistry Techniques, Analytical; Investigative Techniques

Study Officials

• Ehab Mohammad, A. Professor

  Diagnostic radiology department Assiut university hospital

  STUDY DIRECTOR

• Noha Attia, Lecturer

  Diagnostic radiology department Assiut university hospital

  STUDY DIRECTOR

Central Study Contacts

Nafisa Hussein, specialist

CONTACT

+201002688648; nefisahussin@yahoo.com

Samy Khalil, Professor

CONTACT

+201006788053; samy5abdelaziz@yahoo.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: specialist of radiology Assuit University Hospitals

Study Record Dates

• First Submitted: April 24, 2021
• First Posted: April 28, 2021
• Study Start: October 1, 2021
• Primary Completion: October 1, 2022
• Study Completion: December 1, 2022
• Last Updated: September 27, 2021

Record last verified: 2021-09