NCT04862637

Brief Summary

The evidence of swallowing changes in oral cancer patients is still limited. This study aimed to investigated the swallowing changes in these patients by using the videofluoroscopy (VFSS) and high resolution impedance manometry (HRIM).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
48

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Sep 2022

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 21, 2021

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 28, 2021

Completed
1.4 years until next milestone

Study Start

First participant enrolled

September 15, 2022

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 10, 2025

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 11, 2025

Completed
Last Updated

November 19, 2025

Status Verified

September 1, 2025

Enrollment Period

2.7 years

First QC Date

April 21, 2021

Last Update Submit

November 16, 2025

Conditions

Keywords

dysphagiaswallowing

Outcome Measures

Primary Outcomes (1)

  • Bolus presence time

    Lower value indicates shorter bolus presence in the pharynx

    15 minutes during the examination

Eligibility Criteria

Age20 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients with the diagnosis of oral cancer

You may qualify if:

  • patients elective received oral cancer surgery

You may not qualify if:

  • \. patients had major underlying disease, ex: heart, brain, lung, liver disease
  • \. coagulopathy
  • pregnancy
  • \. the patients could not have good compliance

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan University Hospital

Taipei, Taiwan, 100, Taiwan

Location

MeSH Terms

Conditions

Deglutition Disorders

Condition Hierarchy (Ancestors)

Esophageal DiseasesGastrointestinal DiseasesDigestive System DiseasesPharyngeal DiseasesOtorhinolaryngologic Diseases

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
CROSS SECTIONAL
Target Duration
1 Day
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 21, 2021

First Posted

April 28, 2021

Study Start

September 15, 2022

Primary Completion

June 10, 2025

Study Completion

June 11, 2025

Last Updated

November 19, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will not share

ethical concerns

Locations