NCT04860102

Brief Summary

Perineal trauma at the time of vaginal delivery is common, and when the anal sphincter is included, these injuries can be associated with additional morbidity including incontinence, pelvic pain and sexual dysfunction. Techniques studied include hands-on vs hands-off, perineal massage, warm compresses, Ritgen maneuver, and others. It is unclear if a hands-on technique decreases the incidence of perineal trauma compared to a hands-off technique

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started May 2021

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 22, 2021

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 26, 2021

Completed
5 days until next milestone

Study Start

First participant enrolled

May 1, 2021

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 21, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 21, 2021

Completed
Last Updated

December 22, 2021

Status Verified

December 1, 2021

Enrollment Period

8 months

First QC Date

April 22, 2021

Last Update Submit

December 21, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Incidence of Perineal laceration - any degree

    at the time of delivery

Secondary Outcomes (1)

  • Incidence of Episiotomy

    at the time of delivery

Study Arms (2)

hands on

EXPERIMENTAL

Hands-on was defined as involving one hand on the fetal head, applying pressure to control expulsion, with the other hand applying pressure on the maternal perineum

Procedure: hands on

hands off

NO INTERVENTION

standard of care

Interventions

hands onPROCEDURE

Hands-on was defined as involving one hand on the fetal head, applying pressure to control expulsion, with the other hand applying pressure on the maternal perineum

hands on

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility Detailspregnant women
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Singleton gestations
  • Low risk pregnancies
  • to 42 weeks of gestations

You may not qualify if:

  • Multiple gestations
  • Preterm birth

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Gabriele Saccone

Naples, 80100, Italy

Location

Related Publications (2)

  • Trama U, Bernardi FF, Colacurci D, Saccone G, Guida M. Hands-on vs hands-off technique at the time of delivery and postpartum pelvic floor morbidity: a secondary analysis of a randomized clinical trial. Am J Obstet Gynecol MFM. 2024 Jul;6(7):101383. doi: 10.1016/j.ajogmf.2024.101383. Epub 2024 May 21. No abstract available.

  • Califano G, Saccone G, Diana B, Colla Ruvolo C, Ioffredo D, Nappi C, Annella A, Gragnano E, Guida M, Zullo F, Locci M. Hands-on vs hands-off technique for the prevention of perineal injury: a randomized clinical trial. Am J Obstet Gynecol MFM. 2022 Sep;4(5):100675. doi: 10.1016/j.ajogmf.2022.100675. Epub 2022 Jun 10.

MeSH Terms

Interventions

Therapeutic Touch

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsSpiritual Therapies

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

April 22, 2021

First Posted

April 26, 2021

Study Start

May 1, 2021

Primary Completion

December 21, 2021

Study Completion

December 21, 2021

Last Updated

December 22, 2021

Record last verified: 2021-12

Data Sharing

IPD Sharing
Will not share

none planned

Locations