NCT04859049

Brief Summary

infromedial injection of 3 ml local anesthetic drugs and assessing the pain during lacrimal duct intubation and probability of false tracking

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2021

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 4, 2021

Completed
22 days until next milestone

First Posted

Study publicly available on registry

April 26, 2021

Completed
5 months until next milestone

Study Start

First participant enrolled

September 10, 2021

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2022

Completed
Last Updated

September 21, 2022

Status Verified

September 1, 2022

Enrollment Period

1.1 years

First QC Date

April 4, 2021

Last Update Submit

September 16, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Verbal rating scale (VRS) is a 5 point scale from 0 to 4 where 0 is no pain and 4 is unbearable pain

    pain scale

    during surgery , study will started September 2021 & will end November 2022

Secondary Outcomes (1)

  • surgery satisfaction using yes or no questionnaire

    during surgery

Study Arms (2)

Group 1

EXPERIMENTAL

Infra- medial injection of local anesthesia mixture

Procedure: infromedial single injection

Group 2

EXPERIMENTAL

medial canthus injection of the local anesthesia mixture

Procedure: medial canthus injection

Interventions

Group 1: We used a 25G/ 1" length needle to inject 3ml of lidocaine: bupivacaine (1:1) with 30 IU hyaluronic acid, 0.5ml below the inferior punctum in the lower lid medial margin.

Group 1

: We used a 25G/ 1" length needle to inject 3ml of lidocaine: bupivacaine (1:1) with 30 IU hyaluronic acid classical medial canthal injection

Group 2

Eligibility Criteria

Age16 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • adults undergoing lacrimal duct intubation surgery
  • Patients' physical status by the American Association of Anesthesiology (ASA): ASA I, II, III.
  • Age between 18-70, both sexes.
  • Axial lengths ranging between 22-28mm.

You may not qualify if:

  • ASA IV.
  • Patient age less than 18 or more than 70 years.
  • Coagulation disorders (e.g. patients on warfarin (INR\<1.5)
  • Communication difficulties preventing reliable assessment.
  • High myopia (axial length more than 28mm) and medial staphylomas.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Research Institute of Ophthamology

Giza, 12573, Egypt

ENROLLING BY INVITATION

Research Institute of Ophthalmology

Giza, Egypt

RECRUITING

Study Officials

  • abeer salem, MD

    research institute of ophthalmology

    PRINCIPAL INVESTIGATOR

Central Study Contacts

abeer salem, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Researcher of anesthesia

Study Record Dates

First Submitted

April 4, 2021

First Posted

April 26, 2021

Study Start

September 10, 2021

Primary Completion

November 1, 2022

Study Completion

November 1, 2022

Last Updated

September 21, 2022

Record last verified: 2022-09

Data Sharing

IPD Sharing
Will not share

Locations