NCT04848623

Brief Summary

The CoLive Voice research project aims to identify vocal biomarkers of severe conditions and frequent health symptoms. The project is based on digital technologies and statistical algorithms. This is an international anonymous survey where vocal recordings are collected simultaneously with large validated clinical and epidemiological data, in the context of various chronic diseases or frequent health symptoms in the general population.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50,000

participants targeted

Target at P75+ for all trials

Timeline
61mo left

Started Jun 2021

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress49%
Jun 2021May 2031

First Submitted

Initial submission to the registry

April 12, 2021

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 19, 2021

Completed
2 months until next milestone

Study Start

First participant enrolled

June 26, 2021

Completed
4.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2026

Completed
5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2031

Expected
Last Updated

March 30, 2026

Status Verified

February 1, 2026

Enrollment Period

4.8 years

First QC Date

April 12, 2021

Last Update Submit

March 24, 2026

Conditions

Chronic Disease

Keywords

vocal biomarkerdigital biomarkerdigital healthartificial intelligencetelemonitoringmedical devicesprecision health digital biomarker

Outcome Measures

Primary Outcomes (1)

  • Stress

    Patient reported outcome

    At baseline

Secondary Outcomes (8)

  • Fatigue

    At baseline

  • Hypertension

    At baseline

  • Diabetes

    At baseline

  • Migraine

    At baseline

  • Covid-19

    At baseline

  • +3 more secondary outcomes

Eligibility Criteria

Age15 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult and adolescent above 15 years, regardless of their health status and their residence country.

You may qualify if:

  • Adolescents and adults \> 15 years
  • With or without health conditions
  • From all countries

You may not qualify if:

  • Children \< 15 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Luxembourg Institute of Health

Luxembourg, Luxembourg

RECRUITING

Related Publications (1)

  • Elbeji A, Pizzimenti M, Aguayo G, Fischer A, Ayadi H, Mauvais-Jarvis F, Riveline JP, Despotovic V, Fagherazzi G. A voice-based algorithm can predict type 2 diabetes status in USA adults: Findings from the Colive Voice study. PLOS Digit Health. 2024 Dec 19;3(12):e0000679. doi: 10.1371/journal.pdig.0000679. eCollection 2024 Dec.

    PMID: 39700066DERIVED

MeSH Terms

Conditions

Chronic Disease

Condition Hierarchy (Ancestors)

Disease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Guy Fagherazzi, PhD

    LIH

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Aurelie Fischer, MSc

CONTACT

00352621328591aurelie.fischer@lih.lu

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 12, 2021

First Posted

April 19, 2021

Study Start

June 26, 2021

Primary Completion

May 1, 2026

Study Completion (Estimated)

May 1, 2031

Last Updated

March 30, 2026

Record last verified: 2026-02

Locations

LU(1)