Prevalence of Visual Dysfunction in Neurological Disorders

NCT04836715 | Completed

• 1 other identifier: IRB202100649
• Study Type: observational
• Target: 92
• Locations: 1 country
• Sites: 2

Brief Summary

The objective is to determine the prevalence of visual dysfunction in People with Parkinson's Disease (PwP). The investigators will administer the: Visual Impairment in Parkinson's Disease Screen and Revised-Self-Report Assessment of Functional Visual Performance. Patients seen at Fixel Institute and their caregivers will be invited to participate. Responses to the 2 questionnaires will help determine prevalence rates of visual dysfunction in PwP compared to those both with and without other neurological conditions.

Conditions

Parkinson Disease; Other Neurological Disorders; Healthy

Outcome Measures

Primary Outcomes (2)

• Visual Dysfunction

  Determined from VIPDQ: (with the highest and lowest scores on the VIPD-Q Score). Answers are given on a 4-point Likert scale ranging from "never have problems" to "daily problems"

  1 day

• Functional Visual Performance

  Determined from R-SRA FVP: SRAFVP %

  1 day

Other Outcomes (1)

• Correlations between Visual Dysfunction and Functional Visual Performance

  1 day

Study Arms (3)

Parkinson's Disease

Individuals with idiopathic Parkinson's Disease and no other neurological disease

Other Neurological Disorders

Individuals with one neurological disorder other than Parkinson's Disease (e.g. Multiple Sclerosis, Amyotrophic Lateral Sclerosis, Traumatic Brain Injury, Parkinsonism)

Healthy

Individuals without any neurological disorder

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

1. Persons with Parkinson's Disease 2. Persons without a Neurological Condition (Controls) 3. Persons with Other Neurological Conditions (e.g. ALS, TBI, MS, CBT/CBS, MSA, PSP, MCI, etc).

You may qualify if:

• Persons with Parkinson's Disease: Confirmed diagnosis of Parkinson's Disease without presence of any other neurological condition.
• Persons without Parkinson's Disease (Controls): No previous diagnosis of any neurological condition
• Persons with a single other neurological disorder (Neuro Controls): Confirmed diagnosis of other neurological condition (e.g. ALS, multiple sclerosis, essential tremor, ataxia, etc).

You may not qualify if:

• Children (ages younger than 18 years of age)
• Persons with more than one diagnosed neurological condition.

Sponsors & Collaborators

• University of Florida: lead

Study Sites (2)

UF Health Rehab - Fixel Institute

Gainesville, Florida, 32608, United States

Location

University of Florida

Gainesville, Florida, 32608, United States

Location

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases

Study Officials

• Nicole J Tester, PhD, MOT, OTR/L, MSCS

  University of Florida/UF Health Rehab

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 5, 2021
• First Posted: April 8, 2021
• Study Start: January 10, 2021
• Primary Completion: December 1, 2023
• Study Completion: December 1, 2023
• Last Updated: June 12, 2024

Record last verified: 2024-06

Locations

US (2)