Measuring Beliefs and Norms About Persons With Alcohol Use Disorder

NCT04832321 | Completed

• 1 other identifier: 2013P000395_1
• Study Type: interventional
• Target: 1,363
• Locations: 1 country
• Sites: 1

Brief Summary

Survey experiment to estimate drivers of stigma toward people with alcohol use disorder

Conditions

Alcohol Use Disorder (AUD)

Keywords

Stigma

Outcome Measures

Primary Outcomes (6)

• Social Distance

  Willingness to have the man portrayed in the vignette to marry into the study participant's family (single item, culturally adapted instrument developed specifically for this study; response options yes/no)

  Baseline (The experimental manipulation in this study has to do with which version of the survey the study participant receives, so the time frame for assessment is immediate)

• Perceived Norms about Social Distance

  Study participant's perception of the extent to which other people would be willing to have the man portrayed in the vignette to marry into their families (single item, culturally adapted instrument developed specifically for this study; response options on a Likert-type scale: 1=all or almost all; 2=more than half but less than all; 3=fewer than half but more than no one; 4=very few or no one)

  Baseline (The experimental manipulation in this study has to do with which version of the survey the study participant receives, so the time frame for assessment is immediate)

• Negative Attitudes (Attribution)

  Personal belief that the symptoms of the man portrayed in the vignette represent divine punishment (single item, culturally adapted instrument developed specifically for this study; response options yes/no)

  Baseline (The experimental manipulation in this study has to do with which version of the survey the study participant receives, so the time frame for assessment is immediate)

• Perceived Norms about Negative Attitudes (Attribution)

  Study participant's perception of the extent to which other people believe that the symptoms of the man portrayed in the vignette represent divine punishment (single item, culturally adapted instrument developed specifically for this study; response options on a Likert-type scale: 1=all or almost all; 2=more than half but less than all; 3=fewer than half but more than no one; 4=very few or no one)

  Baseline (The experimental manipulation in this study has to do with which version of the survey the study participant receives, so the time frame for assessment is immediate)

• Negative Attitudes (Shame)

  Personal belief that the symptoms of the man portrayed in the vignette bring shame upon his family (single item, culturally adapted instrument developed specifically for this study; response options yes/no)

  Baseline (The experimental manipulation in this study has to do with which version of the survey the study participant receives, so the time frame for assessment is immediate)

• Perceived Norms about Negative Attitudes (Shame)

  Study participant's perception of the extent to which other people believe that the symptoms of the man portrayed in the vignette bring shame upon his family (single item, culturally adapted instrument developed specifically for this study; response options on a Likert-type scale: 1=all or almost all; 2=more than half but less than all; 3=fewer than half but more than no one; 4=very few or no one)

  Baseline (The experimental manipulation in this study has to do with which version of the survey the study participant receives, so the time frame for assessment is immediate)

Study Arms (7)

No intervention: V1: Control

NO INTERVENTION

This version of the survey questionnaire depicts a young man with no symptoms of alcohol use disorder

Experimental: V2: Alcohol Use Disorder

EXPERIMENTAL

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young man with symptomatic, untreated alcohol use disorder.

Other: Survey questionnaire

Experimental: V3: Alcohol Use Disorder + Treatment with Response

EXPERIMENTAL

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young man with symptomatic, untreated alcohol use disorder who is successfully treated with complete response.

Other: Survey questionnaire

Experimental: V4: Alcohol Use Disorder + Treatment with Relapse

EXPERIMENTAL

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young man with symptomatic, untreated alcohol use disorder who is successfully treated with partial relapse.

Other: Survey questionnaire

Experimental: V5: Alcohol Use Disorder + Economic Impact

EXPERIMENTAL

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young man with symptomatic, untreated alcohol use disorder whose untreated alcohol use disorder negatively affects his family's finances.

Other: Survey questionnaire

Experimental: V6: Alcohol Use Disorder + Economic Impact + Treatment with Response

EXPERIMENTAL

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young man with symptomatic, untreated alcohol use disorder whose untreated alcohol use disorder negatively affects his family's finances, who is then successfully treated with complete response.

Other: Survey questionnaire

Experimental: V7: Alcohol Use Disorder + Economic Impact + Treatment with Relapse

EXPERIMENTAL

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young man with symptomatic, untreated alcohol use disorder whose untreated alcohol use disorder negatively affects his family's finances, who is then successfully treated with partial relapse and continued negative economic impact.

Other: Survey questionnaire

Interventions

Survey questionnaire OTHER

Each version of the questionnaire portrays a young Ugandan man with different profiles of illness severity, treatment, and treatment response.

Experimental: V2: Alcohol Use Disorder; Experimental: V3: Alcohol Use Disorder + Treatment with Response; Experimental: V4: Alcohol Use Disorder + Treatment with Relapse; Experimental: V5: Alcohol Use Disorder + Economic Impact; Experimental: V6: Alcohol Use Disorder + Economic Impact + Treatment with Response; Experimental: V7: Alcohol Use Disorder + Economic Impact + Treatment with Relapse

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• All adults who consider Nyakabare their primary place of residence and who are capable of providing consent

You may not qualify if:

• Minors younger than 18 years of age, with the exception of emancipated minors
• Persons who do not consider Nyakabare Parish their primary place of residence, e.g., persons who happen to be visiting Nyakabare at the time of the survey or who own a home in Nyakabare but spend most of their time outside the parish
• Persons with psychosis, neurological damage, acute intoxication, or other cognitive impairment (all of which are determined informally in the field by non-clinical research staff in consultation with a supervisor)

Sponsors & Collaborators

• Massachusetts General Hospital: lead
• Mbarara University of Science and Technology: collaborator

Study Sites (1)

Mbarara University of Science and Technology

Mbarara, Uganda

Location

MeSH Terms

Conditions

Alcoholism; Social Stigma

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Alcohol-Related Disorders; Substance-Related Disorders; Chemically-Induced Disorders; Mental Disorders; Social Behavior; Behavior

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Alexander C Tsai, MD

  Massachusetts General Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Masking Details: Study participants are randomly assigned to be read vignettes with slight changes in wording. Neither study participants nor outcomes assessors are provided with information about "treatment" assignment.
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Psychiatry

Study Record Dates

• First Submitted: April 1, 2021
• First Posted: April 5, 2021
• Study Start: February 19, 2021
• Primary Completion: August 15, 2022
• Study Completion: August 15, 2022
• Last Updated: October 19, 2023

Record last verified: 2023-10

Data Sharing

• IPD Sharing: Will not share

Locations

UG (1)