NCT04826757

Brief Summary

Common low back pain affects about 23% of general population and can be associated with psychosocial difficulties and prolonged inability to work. Its management in France mainly depends on general practioners, and sometime on physiotherapists. A coordinated care between general practioners, physiotherapists and occupational health services would help to improve the care pathway for patients and health professionals. The main objective is to assess the impact of coordinated primary care and deployed at the territories' level, in subacute or acute recurrent low back pain patients in comparison with the standard care.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
500

participants targeted

Target at P75+ for not_applicable low-back-pain

Timeline
19mo left

Started Sep 2022

Longer than P75 for not_applicable low-back-pain

Geographic Reach
1 country

20 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress70%
Sep 2022Nov 2027

First Submitted

Initial submission to the registry

March 3, 2021

Completed
29 days until next milestone

First Posted

Study publicly available on registry

April 1, 2021

Completed
1.5 years until next milestone

Study Start

First participant enrolled

September 21, 2022

Completed
4.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2026

Expected
1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

November 25, 2027

Last Updated

September 19, 2025

Status Verified

September 1, 2025

Enrollment Period

4.1 years

First QC Date

March 3, 2021

Last Update Submit

September 15, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Perceived inability at 1 year

    Ratio of patient presenting improvement equal or above 4 points of Roland Morris Disability Questionnaire. The minimum value of Roland Morris Disability Questionnaire is 0 and the maximun value is 24. A higher score mean worse outcome

    Enrollment to 12 months follow up

Secondary Outcomes (25)

  • Perceived inability

    Enrollment to 3 months follow up, Enrollment to 6 months follow up

  • Roland Morris Disability score over time

    Enrollment, 3 months, 6 months, 12 months

  • Pain perceived

    Enrollment - 3 months , Enrollment - 6 months and Enrollment -12 months

  • Numerical pain scale over time

    Enrollment, 3 months, 6 months, 12 months

  • Occupational status

    at 3 months, 6 months and 12 months

  • +20 more secondary outcomes

Study Arms (2)

standard care

NO INTERVENTION

standard care for low back pain management by general practioners (GPs). the physiotherapist and occupational health services can be solicited independently by the patient or GP.

coordinated care

EXPERIMENTAL

Coordinated care between general practioners, physiotherapist and occupational health services. An intervention training will be performed before the start of the study for any care professional's to elaborate coordination tools and have an active communication.

Other: Coordinated care

Interventions

Coordinated care between general practioners; physiotherapists and occupational health services. Early contact with occupational health service by the general practioner and use of occupational retention tool Active physiotherapy (Individual active, intensive and regular rehabilitation program with 15 sessions of 1 hour, at a rate of 2 or 3 sessions per week)

coordinated care

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patient consulting an investigator GP for subacute low back pain or acute recurrent low back pain
  • Patient with occupational activity (including sick leave)
  • Patient depending of occupational health service
  • Obtaining the signature of the consent to participate in this trial
  • Patient Registered with social security scheme
  • Specific low back pain (fracture, infection, osteoporosis, inflammatory disease, tumor)
  • Low back pain with sciatic, cruralgia
  • Contraindication to active reeducation
  • Impossibility to follow up during 12 months
  • Patient planning to retire within the 12 months following the enrollment
  • Disability to write or read french
  • Adult patient protected under the law (guardianship),
  • Pregnant, breastfeeding or parturient women
  • Persons deprived of their liberty by judicial or administrative decision
  • Persons subject to legal protection measures
  • +3 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (20)

Cluster Bonchamp

Bonchamp-lès-Laval, France

RECRUITING

Cluster Vaunoise

Breteil, France

RECRUITING

Cluster BRULON

Brûlon, France

RECRUITING

Cluster Château Gontier

Château-Gontier, France

RECRUITING

Cluster Châteauneuf sur Sarthe / Morannes

Châteauneuf-sur-Sarthe, France

RECRUITING

Cluster Clisson

Clisson, France

RECRUITING

Cluster Conlie

Conlie, France

RECRUITING

Cluster Craon Renaze Cosse

Craon, France

RECRUITING

Cluster Entrammes Laval

Entrammes, France

RECRUITING

Cluster Roche sur Yon

La Roche-sur-Yon, France

RECRUITING

Cluster Chantenay

Nantes, France

RECRUITING

Cluster Dinan / Quévert / Plouasne

Quévert, France

RECRUITING

Cluster Rennes Beauregard

Rennes, France

RECRUITING

Cluster Rennes Villejean

Rennes, France

RECRUITING

Cluster Les Collines

Roquefort-les-Pins, France

ACTIVE NOT RECRUITING

Cluster St Florent, Mauges, Possonnière

Saint-Florent-le-Vieil, France

RECRUITING

Cluster Savenay

Savenay, France

RECRUITING

Cluster SEGRE

Segré, France

RECRUITING

Cluster Angers- Trélazé

Trélazé, France

RECRUITING

Cluster Vence

Vence, France

RECRUITING

Related Publications (1)

  • Ramond-Roquin A, Begue C, Vizzini J, Chhor S, Bouchez T, Parot-Schinkel E, Loiez A, Petit A, Ghali M, Peurois M, Bouton C. Effectiveness of coordinated care to reduce the risk of prolonged disability among patients suffering from subacute or recurrent acute low back pain in primary care: protocol of the CO.LOMB cluster-randomized, controlled study. Front Med (Lausanne). 2023 Jun 20;10:1156482. doi: 10.3389/fmed.2023.1156482. eCollection 2023.

MeSH Terms

Conditions

Low Back Pain

Condition Hierarchy (Ancestors)

Back PainPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Aline RAMOND ROQUIN, MD-PHD

    Department of Family Medicine - University of Angers

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Aline RAMOND ROQUIN, MD-PHD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Model Details: Randomised, controlled, cluster trial. the project is multicentered.
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 3, 2021

First Posted

April 1, 2021

Study Start

September 21, 2022

Primary Completion (Estimated)

October 31, 2026

Study Completion (Estimated)

November 25, 2027

Last Updated

September 19, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will share

Data will be shared upon reasonable request. Only de-identified data will be shared. Any data collected during the study may be shared. The protocol will be shared initially. Other documents may be shared at a later date upon request (e.g., the CRF to allow a collaborator to select the data they wish to access). The recipients of the data will be researchers. The data will be available for any purpose deemed relevant by the study investigator, based on a protocol provided by the requester, after verification of the obtaining of regulatory approvals, including the favorable opinion of an ethics committee.

Shared Documents
STUDY PROTOCOL
Time Frame
The data will be shared after signing a negotiated data transfer agreement ( data access agreement), for the duration specified in the agreement.
Access Criteria
The data will be made available via secure transfer (sharing platform approved by the university hospital: BlueFiles or Oodrive).

Locations