NCT04824755

Brief Summary

Children after congenital cataract surgery experience a lower quality of life and reduced functional vision. Their families have also been seriously affected. Investigators should pay more attention to them, and measures should be administered to families.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
166

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jul 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2020

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2020

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2021

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

March 1, 2021

Completed
1 month until next milestone

First Posted

Study publicly available on registry

April 1, 2021

Completed
Last Updated

April 1, 2021

Status Verified

March 1, 2021

Enrollment Period

5 months

First QC Date

March 1, 2021

Last Update Submit

March 30, 2021

Conditions

Outcome Measures

Primary Outcomes (8)

  • Gender of Child

    female,male

    through study completion, an average of half a year

  • Parent/legal guardian Age

    under 25,26-30,31-35,36-40,over 41

    through study completion, an average of half a year

  • Parent/legal guardian completing questionnaires

    father,mother,legal guardian

    through study completion, an average of half a year

  • Native Place

    city,not the city

    through study completion, an average of half a year

  • Parent/legal guardian highest level of education

    Primary school graduate,Junior-high graduate/technology secondary school graduate,high school graduate/junior college degree,College graduate,Postgraduate/professional degree

    through study completion, an average of half a year

  • Staging operation

    primary IOL implantation, aphakia, secondary IOL implantation;using questionnaire and telephone follow-up

    through study completion, an average of half a year

  • Postoperative timing

    Less than 1 year,1 to 2 years,2 to 3 years,More than 3 years;using questionnaire and telephone follow-up

    through study completion, an average of half a year

  • Amblyopia treatment

    Cooperative,Average,Uncooperative,No treatment;using questionnaire and telephone follow-up

    through study completion, an average of half a year

Study Arms (4)

Demographics and clinic characteristics of children in different ages

EXPERIMENTAL
Procedure: Yune Zhao

PedEyeQ domain scores

EXPERIMENTAL
Procedure: Yune Zhao

Boxes represent first, median, and third quartile values.

EXPERIMENTAL
Procedure: Yune Zhao

Parent of kids aged 0-4y and 5-11y PedEyeQ domain scores

EXPERIMENTAL
Procedure: Yune Zhao

Interventions

Yune ZhaoPROCEDURE

Yune Zhao did congenital cataract surgeries

Boxes represent first, median, and third quartile values.Demographics and clinic characteristics of children in different agesParent of kids aged 0-4y and 5-11y PedEyeQ domain scoresPedEyeQ domain scores

Eligibility Criteria

Age0 Years - 11 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • visually not significant cataract, and ophthalmic surgery (incisional or laser) within one month

You may not qualify if:

  • parents who were inability to communicate were also excluded

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ophthalmology and Optometry Hospital

Wenzhou, Zhejiang, 325027, China

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Director

Study Record Dates

First Submitted

March 1, 2021

First Posted

April 1, 2021

Study Start

July 1, 2020

Primary Completion

November 30, 2020

Study Completion

January 1, 2021

Last Updated

April 1, 2021

Record last verified: 2021-03

Locations