Oral Manifestation in Patients With SARS-CoV2 Infection.

NCT04821986 | Completed

• 1 other identifier: Oral SARS-CoV2
• Study Type: observational
• Target: 583
• Locations: 1 country
• Sites: 1

Brief Summary

The oral cavity is particularly susceptible to viral infection with several viruses such as herpes simplex virus, cytomegalovirus and Zika virus because of its structures, especially salivary glands and soft tissues Moreover, oral mucosa can be affected by secondary pathological process of a bacterial or fungal nature due to viral immunosuppression. The oral cavity could be considered a "biological barometer" of both viral infection and viral immunosuppression advancement .

Conditions

SARS-CoV Infection

Keywords

oral Manifestation; SARS-CoV2; prevelance

Outcome Measures

Primary Outcomes (1)

• oral manifestation

  describe the patient oral manifestation

  one week

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Patients with SARS-CoV2 infection confirmed with PCR will be recruited form 3 different isolation hospitals at Ministry of health and population. Patient selection will be based on certain inclusion and exclusion criteria.

You may qualify if:

• A diagnosis of SARS-CoV2 with PCR.
• Age range from 18-60 years old

You may not qualify if:

• Pregnancy or contraceptive pills
• Lactation
• Any auto-immune disease that could affect the oral mucosa
• On any neoplastic therapy.
• Uncontrolled diabetes

Sponsors & Collaborators

• Fayoum University: lead

Study Sites (1)

Faculty of Dentistry

Al Fayyum, 63514, Egypt

Location

Related Publications (2)

• La Rosa GRM, Libra M, De Pasquale R, Ferlito S, Pedulla E. Association of Viral Infections With Oral Cavity Lesions: Role of SARS-CoV-2 Infection. Front Med (Lausanne). 2021 Jan 14;7:571214. doi: 10.3389/fmed.2020.571214. eCollection 2020.

  PMID: 33521007 RESULT

• Halboub E, Al-Maweri SA, Alanazi RH, Qaid NM, Abdulrab S. Orofacial manifestations of COVID-19: a brief review of the published literature. Braz Oral Res. 2020 Oct 30;34:e124. doi: 10.1590/1807-3107bor-2020.vol34.0124. eCollection 2020.

  PMID: 33146320 RESULT

MeSH Terms

Conditions

Severe Acute Respiratory Syndrome; Oral Manifestations

Condition Hierarchy (Ancestors)

Respiratory Tract Infections; Infections; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Virus Diseases; Respiratory Tract Diseases; Mouth Diseases; Stomatognathic Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: associate professor in oral & maxillofacial Surgery Department

Study Record Dates

• First Submitted: March 29, 2021
• First Posted: March 30, 2021
• Study Start: April 1, 2021
• Primary Completion: September 30, 2021
• Study Completion: October 15, 2021
• Last Updated: November 5, 2021

Record last verified: 2021-11

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)