Atrial Fibrillation and Carotid Atherosclerosis in Ischemic Stroke Patients-(AFCAS)

NCT04821700 | Unknown

• 1 other identifier: AFCAS 2021
• Study Type: observational
• Target: 3,000
• Locations: 1 country
• Sites: 1

Brief Summary

The main aim of the study is to investigate the prevalence and characteristics of ischemic stroke patients with atrial fibrillation and concurrent carotid atherosclerosis. Additionally, this study will investigate the effect of concurrent carotid atherosclerosis on the outcomes of recurrent stroke, myocardial infarction and death during follow-up

Conditions

Ischemic Stroke; Atrial Fibrillation; Carotid Stenosis

Keywords

Ischemic Stroke; Atrial fibrillation; carotid stenosis; atherosclerosis

Outcome Measures

Primary Outcomes (3)

• Stroke recurrence

  From date of randomization until the date of stroke recurrence, assessed up to 60 months

• Myocardial infarction

  From date of randomization until the date of myocardial infarction, assessed up to 60 months

• Death during follow-up

  From date of randomization until the date of death from any cause, assessed up to 60 months

Secondary Outcomes (1)

• modified Rankin Scale at 3 months

  3 months

Study Arms (2)

Patients with Carotid stenosis

Ischemic stroke patients with atrial fibrillation and carotid stenosis

Biological: Carotid Stenosis

Patients without Carotid stenosis

Ischemic stroke patients with atrial fibrillation without carotid stenosis

Interventions

Carotid Stenosis BIOLOGICAL

To investigate if the concurrent presence of carotid stenosis has any effect on future outcomes of patients with ischemic stroke and atrial fibrillation

Patients with Carotid stenosis

Eligibility Criteria

• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Ischemic Stroke patients with atrial fibrillation

You may qualify if:

• Hospitalization due to ischemic stroke
• Atrial fibrillation
• Αny type of carotid vascular imaging

You may not qualify if:

• Intracerebral haemorrhage on admission
• Haemorrhagic transformation on admission

Sponsors & Collaborators

• University of Thessaly: lead

Study Sites (1)

Medical School, University of Thessaly, Larissa University Hospital

Larissa, 41110, Greece

Location

MeSH Terms

Conditions

Ischemic Stroke; Atrial Fibrillation; Carotid Stenosis; Atherosclerosis

Condition Hierarchy (Ancestors)

Stroke; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Arrhythmias, Cardiac; Heart Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Carotid Artery Diseases; Arterial Occlusive Diseases; Arteriosclerosis

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: March 21, 2021
• First Posted: March 29, 2021
• Study Start: March 20, 2020
• Primary Completion: March 25, 2021
• Study Completion: April 5, 2021
• Last Updated: March 29, 2021

Record last verified: 2021-03

Locations

GR (1)