Radio/Pathological Evaluation of Tongue Cancer Infiltration

NCT04821128 | Unknown

• 1 other identifier: 242
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to assess the good correlation and prediction of the DOI for the post-operative pathological results and prognosis.

Conditions

Oral Squamous; Cell Carcinoma

Keywords

DOI; Infiltration; Oral cavity cancer; OSCC; Tongue cancer; CT scanner

Outcome Measures

Primary Outcomes (1)

• The primary outcome will be the measure of the correlation of the depth of invasion on the radiological pre operative images and of the pathological analyses on the resection piece.

  With a Bland Altman analysis we will assess the good correlation between the pre and post operatory mesures of the depth of invasion in the oral squamous cell carcioma

  The outcome will be measured at the inclusion of the patient in the current study.

Study Arms (1)

Patients who improved surgical treatment for oral cavity cancer

T1 T2 and T3 OSCC tumor, patients who have a recent evaluation cervico thoracic scanner in their medical files.

Other: Radiologic and pathological review.

Interventions

Radiologic and pathological review. OTHER

We will analyse the pre operative scannographic and MRI (if available) images, and the post operative pathological analyses. The scanners will be reviewed by 2 well trained clinicians (one head and neck radiologist and one head and neck surgeon). Then we will analyse the correlation between the radiological and the pathological analysis.

Patients who improved surgical treatment for oral cavity cancer

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The population will include all the patients chirurgically treated for an OSCC for 2014 to 2019, who have a pre operativ scanner at least in their medical file. We will exclude the T4, the patients with very artefacted exams, and those with R+ resections.

You may qualify if:

• patients chirurgically treated for an OSCC
• T1 T2 T3
• CT scanner in their medical file

You may not qualify if:

• R+ résection
• Artefacts on CT scanner

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

Croix rousse hospital

Lyon, 69004, France

RECRUITING

MeSH Terms

Conditions

Mouth Neoplasms; Tongue Neoplasms

Interventions

X-Rays

Condition Hierarchy (Ancestors)

Head and Neck Neoplasms; Neoplasms by Site; Neoplasms; Mouth Diseases; Stomatognathic Diseases; Tongue Diseases

Intervention Hierarchy (Ancestors)

Electromagnetic Radiation; Electromagnetic Phenomena; Magnetic Phenomena; Physical Phenomena; Radiation; Radiation, Ionizing

Central Study Contacts

Leonard MEGUERDITCHIAN, MD

CONTACT

6 10 46 17 70; leonard.meguerditchian-hoffmeyer@chu-lyon.fr

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 25, 2021
• First Posted: March 29, 2021
• Study Start: November 27, 2020
• Primary Completion: November 27, 2020
• Study Completion: May 27, 2021
• Last Updated: March 29, 2021

Record last verified: 2021-03

Locations

FR (1)