Assessment of Remote Vital Signs for Telemedicine Applications

NCT04820387 | Active Not Recruiting

• 1 other identifier: IRB00252571
• Study Type: observational
• Target: 94
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine whether vital signs can be extracted from video. A secondary purpose is to create a database, including raw video, of "ground truth" physiological data on human subjects in order to test current and/or future approaches developed to extract vital signs from video. This research may have an immediate impact on not only the assessment of risk for COVID-19 but also may provide a significant technological enhancement to Johns Hopkins Medicine's telemedicine capabilities.

Conditions

Telemedicine; Physiology

Keywords

Telemedicine; Physiology; Vital Signs

Outcome Measures

Primary Outcomes (1)

• Quantification of SpO2 (percentage) from video

  The principal outcome is the capability to calculate a reliable and clinically useful measure of blood oxygenation from video. Our objective is to quantify SpO2 from video within +/- 0.5% from clinical standard.

  3 years

Secondary Outcomes (1)

• Clinical quality data obtained via contact sensors

  3 years

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Convenience

You may qualify if:

• Age: 18-75
• Fluent in English
• Normal or corrected-to-normal vision
• Able to participate in study activities
• Passed Johns Hopkins Medicine Outpatient Office COVID-19 screening checklist within 24 hours of study visit.

You may not qualify if:

• Hospitalization for heart failure, stroke or major cardiac event (myocardial infarction) within past 3 months.
• History of chest pain during exercise (angina).
• High blood pressure needing more than 1 medication for treatment.
• Blood pressure at rest exceeding systolic blood pressure (SBP) 150 millimeters of Mercury (mmHg), diastolic blood pressure (DBP) 100 mmHg.
• Heart rate at rest exceeding 100 beats per minute (bpm).
• Abnormal ECG, indwelling pacemaker or cardiac defibrillator.
• Home oxygen prescription.
• Women who or are pregnant or suspect they may be pregnant.

Sponsors & Collaborators

• Johns Hopkins University: lead
• eMedicalSentry: collaborator
• Applied Physics Laboratory: collaborator

Study Sites (1)

Johns Hopkins Asthma & Allergy Center

Baltimore, Maryland, 21224, United States

Location

Study Officials

• Edward Chen, MD

  Johns Hopkins University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 24, 2021
• First Posted: March 29, 2021
• Study Start: April 20, 2021
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: September 11, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)