Perioperative Cardiac Complications in Noncardiac Surgery in Tibet, China
Evaluation of Perioperative Cardiac Complications in Noncardiac Surgery in Tibet Autonomous Region in China：the Incidence, Risk Factors and Cardiac Troponin Monitoring
1 other identifier
observational
700
1 country
1
Brief Summary
This observational study will describe the incidence and risk factors of perioperative cardiac complications (PCCs) in patients undergoing non-cardiac surgery in Tibet Autonomous Region. And perioperative troponin monitoring will be implemented in these population.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Apr 2021
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 24, 2021
CompletedFirst Posted
Study publicly available on registry
March 29, 2021
CompletedStudy Start
First participant enrolled
April 1, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2022
CompletedMarch 29, 2021
March 1, 2021
1.3 years
March 24, 2021
March 26, 2021
Conditions
Outcome Measures
Primary Outcomes (1)
Perioperative cardiac complications
Perioperative cardiac complications are defined as acute coronary syndrome (ACS), heart failure, new-onset severe arrhythmia, nonfatal cardiac arrest, and cardiac death. ACS included ST-elevation myocardial infarction (STEMI) and non-ST-elevation acute coronary syndrome (NSTE-ACS). NSTE-ACS could be further subdivided into non-ST-elevation myocardial infarction and unstable angina according to the cardiac biomarkers.
Participants will be followed for 30 days after surgery
Interventions
cTnI will be measured at baseline prior to surgery, as well as on 1h,12h, 24h and 72h after surgery for each patient in study B.
Eligibility Criteria
Patients aged 50 years or older undergoing intermediate to high-risk elective noncardiac surgery.
You may qualify if:
- Patients aged 50 years or older；
- Undergoing intermediate to high-risk elective noncardiac surgery .
You may not qualify if:
- Emergency surgery;
- Local anesthesia;
- Low-risk surgery;
- ASA classification V or VI
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Peking Union Medical College Hospital
Beijing, China
Related Publications (1)
Zhu Q, Duan H, Liu Z, Li Y, Zhang Y, Labaciren, Shen L, Huang Y. The incidence and risk factors of perioperative cardiac complications in noncardiac major surgery in high-altitude areas: A prospective trial in Tibet autonomous region, China. Front Cardiovasc Med. 2023 Apr 3;10:1158711. doi: 10.3389/fcvm.2023.1158711. eCollection 2023.
PMID: 37077733DERIVED
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 24, 2021
First Posted
March 29, 2021
Study Start
April 1, 2021
Primary Completion
August 1, 2022
Study Completion
December 1, 2022
Last Updated
March 29, 2021
Record last verified: 2021-03
Data Sharing
- IPD Sharing
- Will share