A Cross Sectional Observational Study on Relation Between Oral Manifestation and Hepatitis C in Egypt

NCT04812990 | Completed

• 1 other identifier: HC IN EGYPT
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Hepatitis C virus (HCV) is the major cause of chronic liver disease and has a long-term resultant complications4 and it considered as a major endemic medical health problem in Egypt. It affects multiple organs and reflect various manifestations on oral cavity.The purpose of this study is to assess the prevalence of oral mucosa conditions, type of oral manifestation and gingival lesions in patients with hepatitis C

Conditions

Hepatitis C; Oral Manifestations; in Egyptian Population

Outcome Measures

Primary Outcomes (1)

• oral lesion relation to hepatitis c

  the prevalence to oral lesions related to hepatitis C patients

  six months

Study Arms (2)

hepatitis c patients

50 patients will be recruited for study group from consecutive patients previously diagnosed by hepatitis C regardless of the etiology of the condition and regularly attending at Soad Kafay hospital. Participants with history of smoking and alcoholism that could affect their oral health status were excluded.

clinically healthy patients

populations will be randomly recruited from the out-patient of dental diagnosis clinic in Misr University For science \& technology university to include total 50 clinically healthy participants, with no history of liver disease, or any other chronic debilitating illness, or habit of smoking or drinking, , as well as history of an intervention or condition that could affect the oral mucosa (e.g., history of radiotherapy and/or not receiving any medication that could affect oral health.

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

hepatic (virus C) and non hepatic patients on Egyptian population

You may qualify if:

• patients previously diagnosed with hepatits c, with education, ability and willing to participate in the study

You may not qualify if:

• Patients with systemic diseases such as nutritional deficiency; cardiovascular, respiratory, metabolic, and endocrinal disorders; also smoking and alcoholism that could affect their oral health status were excluded. As well as history of an intervention or condition that could affect the oral mucosa (e.g., history of radiotherapy).

Sponsors & Collaborators

• Misr University for Science and Technology: lead

Study Sites (1)

Faculty of dentistry at MUST

Giza, 02, Egypt

Location

MeSH Terms

Conditions

Hepatitis C; Oral Manifestations

Condition Hierarchy (Ancestors)

Blood-Borne Infections; Communicable Diseases; Infections; Hepatitis, Viral, Human; Virus Diseases; Flaviviridae Infections; RNA Virus Infections; Hepatitis; Liver Diseases; Digestive System Diseases; Mouth Diseases; Stomatognathic Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: LECTURER

Study Record Dates

• First Submitted: March 20, 2021
• First Posted: March 24, 2021
• Study Start: March 1, 2021
• Primary Completion: July 4, 2021
• Study Completion: August 1, 2021
• Last Updated: March 20, 2023

Record last verified: 2023-03

Locations

EG (1)