NCT04809298

Brief Summary

In a prospective, randomized, controlled, parallel group study the accuracy, intervention time and radiation dose of CT-guided punctures using the Puncture Cube® will be compared to the conventional free-hand method in patients requiring a percutaneous diagnostic or therapeutic CT-guided intervention for lumbar pain (facet joint-, nerve root-, epidural infiltrations at the lumbar/lumbosacral level).

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
120

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2019

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2019

Completed
1.8 years until next milestone

First Submitted

Initial submission to the registry

March 5, 2021

Completed
17 days until next milestone

First Posted

Study publicly available on registry

March 22, 2021

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2022

Completed
Last Updated

April 7, 2022

Status Verified

April 1, 2022

Enrollment Period

3.6 years

First QC Date

March 5, 2021

Last Update Submit

April 6, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Puncture accuracy

    Assessment of puncture accuracy (distance and angle error between planned and achieved trajectory)

    during procedure time approximately 30 min.

Secondary Outcomes (3)

  • Number of control acquisitions to achieve target

    during procedure time approximately 30 min.

  • Assessment of radiation dose

    during procedure time approximately 30 min.

  • Assessment of intervention time

    during procedure time approximately 30 min.

Study Arms (2)

Free-hand lumbar punction

OTHER

Diagnostic or therapeutic CT-guided intervention for lumbar pain management using the free-hand method.

Device: Free-hand therapeutic CT-guided punction for lumbar pain

Puncture Cube

ACTIVE COMPARATOR

Diagnostic or therapeutic CT-guided intervention for lumbar pain management using the Puncture Cube® as a needle navigation device.

Device: Puncture Cube

Interventions

Diagnostic or therapeutic CT-guided intervention for lumbar pain management using the Puncture Cube® as a needle navigation device.

Free-hand lumbar punction

Diagnostic or therapeutic CT-guided intervention for lumbar pain management using the Puncture Cube® as a needle navigation device.

Puncture Cube

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients requiring a percutaneous therapeutic CT-guided intervention for
  • lumbar pain (joint-, nerve root-, epidural infiltrations at the lumbar/lumbosacral level)
  • age ≥ 18 years
  • Signed informed consent prior to intervention

You may not qualify if:

  • Patients suffering from severe obesity (BMI \> 30 kg/m2)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Neuroradiology, Kantonsspital Aarau

Aarau, Canton of Aargau, 5001, Switzerland

RECRUITING

MeSH Terms

Conditions

Low Back Pain

Condition Hierarchy (Ancestors)

Back PainPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Luca Remonda, Prof.

    Department of Neuroradiology, Kantonsspital Aarau

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Luca Remonda, Prof.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Prospective, randomized, controlled, parallel group study
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Prof. Dr. med.

Study Record Dates

First Submitted

March 5, 2021

First Posted

March 22, 2021

Study Start

June 1, 2019

Primary Completion

December 31, 2022

Study Completion

December 31, 2022

Last Updated

April 7, 2022

Record last verified: 2022-04

Data Sharing

IPD Sharing
Will not share

Locations