How Does Smoking Effect the Clinical Performance of a Universal Adhesive Used With Different Application Modes in Non Carious Cervical Lesions?
Sponsor study identifier
interventional
47
1 country
1
Study Start
September 1, 2018
Actual (reported)Primary Completion
March 1, 2021
Actual (reported)Study Completion
January 1, 2028
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
The aim of the study was to evaluate the influence of smoking on the clinical performance of a universal adhesive used with different application modes in non-carious cervical lesions.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
January 1, 2028
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 1, 2018
Actual (reported)March 1, 2021
Actual (reported)March 13, 2021
Actual (reported)March 19, 2021
Actual (reported)January 1, 2028
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Retention
According to the usphs criteria, retention indicates whether a restorative material is functional in the oral environment, and is the most important criterion by which we can evaluate the success of the material. Alpha: Retained. Charlie: Mobile or missing; clinically unacceptable.
baseline (one week)-18-month
Marginal Discoloration
Evaluation of color changes in restoration margins and linear staining along restoration margins. Alfa: No discoloration along the margin. Bravo: Slight and superficial staining (removable, usually localized). Charlie: Deep staining cannot be polished away.
baseline (one week)-18-month
Marginal Adaptation
The marginal adaptation criterion evaluates the complete achievement of tooth-restoration integrity. Alpha: Undetectable. Bravo: Visible evidence of a crevice along the margin, dentin not exposed, clinically acceptable. Charlie: Explorer penetrates into crevice, dentin is exposed; clinically unacceptable.
baseline (one week)-18-month
Color match
Evaluating whether the restoration and adjacent tooth tissue color is compatible. Alpha:Matches tooth. Bravo: Acceptable mismatch. Charlie:Unacceptable mismatch.
baseline (one week)-18-month
VAS scale
baseline (one week)-18-month
Plaque Index
baseline (one week)-18-month
Gingival index
baseline (one week)-18-month
Participants who smoke at least 10 cigarettes per day
participants who non-smoke have never smoked before
The phosphoric acid gel was applied to enamel and dentin washed for 5s and was dried gently with air spray. The adhesive system was applied to enamel and dentin surfaces and leave it in place for 10s.
Hacettepe University Faculty of Dentistry
Ankara, 06100, Turkey (Türkiye)
Aydemir G, Gorucu J, Yazici AR. How does smoking affect the clinical performance of a universal adhesive in non-carious cervical lesions? -An 18-month randomized clinical trial. BMC Oral Health. 2026 Aug 4;26(1):1666. doi: 10.1186/s12903-026-09521-x.
A. Ruya Yazici
Study Principal Investigator
47 participants (actual enrollment reported by the registry).
Post-op Hypersensitivity
It is the evaluation of sensitivity after dental treatment. Alpha: Hypersensitivity absent. Charlie: Present; clinically unacceptable.
baseline (one week)-18-month
Secondary Caries
In this criterion, the dark colored area that occurs under the tooth tissue surface and in the tooth tissue adjacent to the restoration is defined as caries. Alpha: Caries absent. Charlie: Present; clinically unacceptable.
baseline (one week)-18-month
The phosphoric acid was applied only on enamel for 10-15s then washed and was gently dried with air spray. The adhesive system was applied to enamel and dentin surfaces.
The adhesive system was applied to the enamel and dentin surfaces.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
First Submitted
March 13, 2021
First Posted
March 19, 2021
Study Start
September 1, 2018
Actual (reported)Primary Completion
March 1, 2021
Actual (reported)Study Completion
January 1, 2028
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
June 26, 2026
Record last verified: 2026-06
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: