NCT04802902

Brief Summary

This observational prospective monosite study aims to describe, for the first time, management in a hospital-at-home programme of patients treated by immunotherapy-chemotherapy combo for bronchial cancer in maintenance phase of first row metastatic treatment. The feasibility in good conditions of this management, the patients' quality of life and their satisfaction will be evaluated. A cost-benefit analysis will be done to compare hospital-at-home programme and classical day hospitalization.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Sep 2021

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 15, 2021

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 17, 2021

Completed
7 months until next milestone

Study Start

First participant enrolled

September 29, 2021

Completed
2.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 8, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 8, 2024

Completed
Last Updated

February 26, 2024

Status Verified

February 1, 2024

Enrollment Period

2.4 years

First QC Date

March 15, 2021

Last Update Submit

February 23, 2024

Conditions

Keywords

immunotherapychimiotherapyBronchial cancerhome-based hospitalization

Outcome Measures

Primary Outcomes (1)

  • Feasibility of home-based immunotherapy (percentage of patients who interrupted their home hospitalization for reasons directly linked to that management)

    Feasibility under good conditions of home-based immunotherapy, defined by the percentage of patients who interrupted their home hospitalization for reasons directly linked to that management.

    1 year

Secondary Outcomes (6)

  • Cost-benefit analysis

    1 year

  • Number of adverse effects occuring during the study

    1 year

  • Number of Incidents occurring during the Hospital at Home program handling process

    1 year

  • Quality of Life Questionnaire (EORTC QLQ-C30) total score

    at inclusion, month 3, 6 9 and 12

  • Patients' Satisfaction Questionnaire

    at month 3, 6 9 and 12

  • +1 more secondary outcomes

Interventions

management in a hospital-at-home programme of patients treated by immunotherapy and chimiotherapy combo for bronchial cancer

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients treated by immunotherapy and chemotherapy combo in maintenance phase for bronchial cancer

You may qualify if:

  • Patients aged 18 and over,
  • with bronchial metastatic cancer treated in first row maintenance phase by immunotherapy-chemotherapy combo,
  • having at least one assessments of the response to immunotherapy received in day hospitalization with efficiency (stability or partial response),
  • without any graded higher than 1 adverse effects, or uncontrolled grade 1 adverse effects related to immunotherapy
  • eligible for a home-based hospitalization

You may not qualify if:

  • Frail patients requiring a frequent medical assessment thus day hospitalization cares

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre hospitalier de pau

Pau, Aquitaine, 64160, France

Location

MeSH Terms

Conditions

Carcinoma, Bronchogenic

Condition Hierarchy (Ancestors)

Bronchial NeoplasmsLung NeoplasmsRespiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 15, 2021

First Posted

March 17, 2021

Study Start

September 29, 2021

Primary Completion

February 8, 2024

Study Completion

February 8, 2024

Last Updated

February 26, 2024

Record last verified: 2024-02

Locations