Game-based Telehealth Therapeutic Intervention in First Onset Psychosis

NCT04799717 | Completed

• 1 other identifier: 59698
• Study Type: observational
• Target: 8
• Locations: 1 country
• Sites: 1

Brief Summary

The goal is to provide combination of 2 hours of weekly game based telehealth therapeutic intervention along with CBT-P for children identified with first onset psychosis or to be clinically high risk for psychosis thus widening therapeutic services offered. Target outcome measures are improvement in clinical symptoms, treatment engagement, and reduced hospitalization rates.

Conditions

Psychotic Disorders; Schizophrenia Spectrum Disorders

Keywords

Telehealth, Therapy, intervention; Video game, CBT-P

Outcome Measures

Primary Outcomes (3)

• Number of Participants with a Hospitalization

  Review patient's medical record for number of hospitalizations due to psychotic disorder

  The 15 week participation period

• Patient Session Engagement

  Measure client engagement in treatment by providing a post-session survey. The survey has four questions to solicit client feedback on the therapy session. The clients will answer on a scale of 1-10 with 1 being the lowest and 10 being the highest score. Add all four numbers together to obtain the total score.

  The 15 week participation period.

• Brief Psychiatric Rating Scale Scores

  Perform the Brief Psychiatric Rating Scale (BPRS). The BPRS is a 21 questionaire of present of mental health symptoms wtih each question scored on a Likert scale of 1-7. A score of 01reflects that a particular question was not assessed and a score of 7 is highest severity of the symptom listed in each individual question. A total score is not calculated.

  The 15 week participation period.

Interventions

Gaming session BEHAVIORAL

Participants will be provided the option to play an online game with the clinician for the first half of the session through an online platform.

Eligibility Criteria

• Age: 10 Years - 18 Years
• Sex: all
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Adolescents and young adults ages 10 to 18 years of age with a psychotic disorder diagnosis or report of transient positive symptoms of psychosis that has lasted more than one week over the past year.

You may qualify if:

• Clinical Diagnosis of Schizophrenia spectrum disorders
• Major Depressive Disorder with Psychotic Features
• Schizophrenia,
• Attenuated psychosis syndrome,
• Brief psychotic disorder,
• Schizoaffective Disorder,
• Schizophreniform disorder
• Unspecified psychotic disorder
• Clinical high risk for psychosis

You may not qualify if:

• Clinical Diagnosis of Intellectual Disability

Sponsors & Collaborators

• Stanford University: lead

Study Sites (1)

Stanford Universtiy

Palo Alto, California, 94305, United States

Location

Related Publications (11)

• Ferrari M, McIlwaine SV, Reynolds JA, Archie S, Boydell K, Lal S, Shah JL, Henderson J, Alvarez-Jimenez M, Andersson N, Boruff J, Nielsen RKL, Iyer SN. Digital Game Interventions for Youth Mental Health Services (Gaming My Way to Recovery): Protocol for a Scoping Review. JMIR Res Protoc. 2020 Jun 24;9(6):e13834. doi: 10.2196/13834.

  PMID: 32579117 BACKGROUND

• Landa Y, Mueser KT, Wyka KE, Shreck E, Jespersen R, Jacobs MA, Griffin KW, van der Gaag M, Reyna VF, Beck AT, Silbersweig DA, Walkup JT. Development of a group and family-based cognitive behavioural therapy program for youth at risk for psychosis. Early Interv Psychiatry. 2016 Dec;10(6):511-521. doi: 10.1111/eip.12204. Epub 2015 Jan 13.

  PMID: 25585830 BACKGROUND

• Peters E, Crombie T, Agbedjro D, Johns LC, Stahl D, Greenwood K, Keen N, Onwumere J, Hunter E, Smith L, Kuipers E. The long-term effectiveness of cognitive behavior therapy for psychosis within a routine psychological therapies service. Front Psychol. 2015 Oct 29;6:1658. doi: 10.3389/fpsyg.2015.01658. eCollection 2015.

  PMID: 26579041 BACKGROUND

• Rasskazova, Elena & Friedberg, Robert. (2016). CBT for psychosis prevention and treatment in youth. Current Psychiatry Reviews. 12.

  BACKGROUND

• Stafford MR, Jackson H, Mayo-Wilson E, Morrison AP, Kendall T. Early interventions to prevent psychosis: systematic review and meta-analysis. BMJ. 2013 Jan 18;346:f185. doi: 10.1136/bmj.f185.

  PMID: 23335473 BACKGROUND

• Stafford MR, Mayo-Wilson E, Loucas CE, James A, Hollis C, Birchwood M, Kendall T. Efficacy and safety of pharmacological and psychological interventions for the treatment of psychosis and schizophrenia in children, adolescents and young adults: a systematic review and meta-analysis. PLoS One. 2015 Feb 11;10(2):e0117166. doi: 10.1371/journal.pone.0117166. eCollection 2015.

  PMID: 25671707 BACKGROUND

• Stain HJ, Bucci S, Baker AL, Carr V, Emsley R, Halpin S, Lewin T, Schall U, Clarke V, Crittenden K, Startup M. A randomised controlled trial of cognitive behaviour therapy versus non-directive reflective listening for young people at ultra high risk of developing psychosis: The detection and evaluation of psychological therapy (DEPTh) trial. Schizophr Res. 2016 Oct;176(2-3):212-219. doi: 10.1016/j.schres.2016.08.008. Epub 2016 Aug 20.

  PMID: 27554197 BACKGROUND

• Adery LH, Ichinose M, Torregrossa LJ, Wade J, Nichols H, Bekele E, Bian D, Gizdic A, Granholm E, Sarkar N, Park S. The acceptability and feasibility of a novel virtual reality based social skills training game for schizophrenia: Preliminary findings. Psychiatry Res. 2018 Dec;270:496-502. doi: 10.1016/j.psychres.2018.10.014. Epub 2018 Oct 9.

  PMID: 30326433 BACKGROUND

• Yang CY, Lee TH, Lo SC, Beckstead JW. The effects of auditory hallucination symptom management programme for people with schizophrenia: a quasi-experimental design. J Adv Nurs. 2015 Dec;71(12):2886-97. doi: 10.1111/jan.12754. Epub 2015 Aug 18.

  PMID: 26283291 BACKGROUND

• Roberts MT, Lloyd J, Valimaki M, Ho GW, Freemantle M, Bekefi AZ. Video games for people with schizophrenia. Cochrane Database Syst Rev. 2021 Feb 4;2(2):CD012844. doi: 10.1002/14651858.CD012844.pub2.

  PMID: 33539561 BACKGROUND

• Freeman D, Reeve S, Robinson A, Ehlers A, Clark D, Spanlang B, Slater M. Virtual reality in the assessment, understanding, and treatment of mental health disorders. Psychol Med. 2017 Oct;47(14):2393-2400. doi: 10.1017/S003329171700040X. Epub 2017 Mar 22.

  PMID: 28325167 BACKGROUND

MeSH Terms

Conditions

Psychotic Disorders

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders

Study Officials

• Janani Venugopalakrishnan, MD MPH

  Stanford University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical Assistant Professor

Study Record Dates

• First Submitted: February 12, 2021
• First Posted: March 16, 2021
• Study Start: August 31, 2021
• Primary Completion: September 9, 2022
• Study Completion: September 9, 2022
• Last Updated: January 9, 2023

Record last verified: 2023-01

Locations

US (1)