Outcome of Elderly Patients With Appendicitis

NCT04791657 | Completed

• 1 other identifier: Gulhane2021-51
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate factors that predict 30-day complications after the surgical treatment of appendicitis in elderly patients.

Conditions

Appendicitis Acute

Keywords

appendicitis; geriatrics

Outcome Measures

Primary Outcomes (1)

• 30-day postoperative complication rate

  The primary clinical outcome of interest is 30-day postoperative complications. The Clavien-Dindo classification will be used to grade postoperative outcomes and complications

  30 days

Secondary Outcomes (2)

• In-hospital mortality rate

  30 days

• 30-day readmission rate

  30 days

Study Arms (2)

Patients without complications

Patients with uneventful recovery

Procedure: Appendectomy

Patients with complications

Patients experiencing complications within 30 days postoperatively

Procedure: Appendectomy

Interventions

Appendectomy PROCEDURE

Surgical treatment for appendicitis

Patients with complications; Patients without complications

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All patients aged 65 years and older undergoing appendectomy for acute appendicitis are included in this study

You may qualify if:

• Patients aged 65 years and older
• Patients undergoing appendectomy for acute appendicitis (pathologically confirmed)
• Patients having complete records of clinical data and postoperative follow-up records

You may not qualify if:

• Patients younger than 65 years
• Patients undergoing an appendectomy as part of another major operation or those with appendiceal malignancy
• Patients who are treated nonoperatively for acute appendicitis

Sponsors & Collaborators

• Gulhane Training and Research Hospital: lead

Study Sites (1)

Gulhane Training and Research Hospital

Ankara, 06010, Turkey (Türkiye)

Location

Related Publications (4)

• Angeramo CA, Dreifuss NH, Giacone J, Schlottmann F. Outcomes of Acute Appendicitis in Elderly Patients: a Single Center Analysis of 2000 Laparoscopic Appendectomies. J Gastrointest Surg. 2020 Dec;24(12):2859-2861. doi: 10.1007/s11605-020-04726-z. Epub 2020 Aug 31. No abstract available.

  PMID: 32865733 BACKGROUND

• Yang J, Yu K, Li W, Si X, Zhang J, Wu W, Cao Y. Laparoscopic Appendectomy for Complicated Acute Appendicitis in the Elderly: A Single-center Experience. Surg Laparosc Endosc Percutan Tech. 2017 Oct;27(5):366-368. doi: 10.1097/SLE.0000000000000447.

  PMID: 28708770 BACKGROUND

• Hui TT, Major KM, Avital I, Hiatt JR, Margulies DR. Outcome of elderly patients with appendicitis: effect of computed tomography and laparoscopy. Arch Surg. 2002 Sep;137(9):995-8; discussion 999-1000. doi: 10.1001/archsurg.137.9.995.

  PMID: 12215147 BACKGROUND

• Pokharel N, Sapkota P, Kc B, Rimal S, Thapa S, Shakya R. Acute appendicitis in elderly patients: a challenge for surgeons. Nepal Med Coll J. 2011 Dec;13(4):285-8.

  PMID: 23016482 BACKGROUND

MeSH Terms

Conditions

Appendicitis

Interventions

Appendectomy

Condition Hierarchy (Ancestors)

Intraabdominal Infections; Infections; Gastroenteritis; Gastrointestinal Diseases; Digestive System Diseases; Cecal Diseases; Intestinal Diseases

Intervention Hierarchy (Ancestors)

Digestive System Surgical Procedures; Surgical Procedures, Operative

Study Officials

• Suleyman U Celik, MD

  Gulhane Training and Research Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: March 7, 2021
• First Posted: March 10, 2021
• Study Start: January 1, 2017
• Primary Completion: December 31, 2020
• Study Completion: December 31, 2020
• Last Updated: March 10, 2021

Record last verified: 2021-03

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)