NCT04790669

Brief Summary

This project was a Randomized clinical trial conducted on extensor lag in post-operative knee stiffness patient to compare the effects of The Daily Adjustable Progressive Resistive Exercise (DAPRE) technique versus Close kinetic chain (CKC) exercise training in people who had undergone knee stiffness, m so that we can have best treatment option for patients with extensor lag.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
22

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 15, 2020

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

March 6, 2021

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 10, 2021

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 20, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 20, 2021

Completed
Last Updated

September 2, 2021

Status Verified

August 1, 2021

Enrollment Period

7 months

First QC Date

March 6, 2021

Last Update Submit

August 27, 2021

Conditions

Keywords

DAPRECKC exercisesExtensor lag

Outcome Measures

Primary Outcomes (4)

  • Change in knee functional Improvement by WOMAC index

    By using WOMAC index, knee functional improvement was checked at baseline \& post interventional readings at 6th week.

    6 weeks (3 sessions per week).

  • Change in knee range of motion by universal goniometer.

    Change in ROM at baseline \& post interventional readings at 6th week.

    6 weeks (3 sessions per week).

  • Change in pain by 'Numeric Pain Rating Scale'

    Change in pain was measured at baseline \& post interventional readings at 6th week.

    6 weeks (3 sessions per week).

  • Change in strength by Sphygmomanometer

    Change in strength was measured at baseline \& post interventional readings at 6th week.

    6 weeks (3 sessions per week).

Study Arms (2)

Daily adjustable progressive resistance exercises (DAPRE)

EXPERIMENTAL

DAPRE technique, hot pack, stretching exercises.

Procedure: Daily adjustable progressive resistance exercises (DAPRE)

Close kinetic chain exercises (CKC).

EXPERIMENTAL

CKC exercises, hot pack, stretching exercises

Procedure: Close kinetic chain exercises (CKC).

Interventions

Daily adjustable progressive resistance exercises (DAPRE) In Group A, 11 participants were received Conventional physiotherapy treatment in addition to DAPRE technique by leg extension machine. In DAPRE technique, four sets of exercises were performed. The first two sets of exercise consisted of ten and then six repetitions, per- formed against one-half and three-fourths of the previously established working weight. Working weight is the amount of weight a patient uses during an individual session. The full working weight was used on the third set, and the patient performed as many repetitions as possible. After performing each of the third and fourth sets, patients rested for 1 min.6 weeks (3 sessions per week)• Hot pack: 10 min• Stretching of calf and hamstring muscle: 10 min. Assessment was done via WOMAC index, universal goniometer, numeric pain rating scale \& sphygmomanometer.

Daily adjustable progressive resistance exercises (DAPRE)

Close kinetic chain exercises (CKC). In Group B, 11 participants was received Conventional physiotherapy treatment in addition to close kinetic chain exercises. Close kinetic chain exercises for extensor lag was seated leg press, double or single one third knee bend, step up and down exercise, wall slide with weight. Treatment time was 30 minutes and three session per week was applied on alternate day for up to 6 weeks. Pre interventional readings will be taken at baseline \& post interventional readings at 6th week. 6 weeks (3 sessions per week) • Hot pack: 10 min • Stretching of calf and hamstring muscle: 10 min. Assessment was done via WOMAC index, universal goniometer, numeric pain rating scale \& sphygmomanometer.

Close kinetic chain exercises (CKC).

Eligibility Criteria

Age30 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Post-operative knee stiffness (patients with 1-3 month stiffness).
  • Both male and female , age 30-60 years.
  • Willing to participate in research.

You may not qualify if:

  • Pre-operative knee stiffness
  • Severe cardiopulmonary disease
  • Patients undergoing chemotherapy
  • Any traumatic injury/ Acute inflammatory muscular pathology
  • TKR \& hip pathology and replacement
  • Meniscal tear

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Riphah International University

Lahore, Punjab Province, 54000, Pakistan

Location

Related Publications (3)

  • Ardali G. A daily adjustable progressive resistance exercise protocol and functional training to increase quadriceps muscle strength and functional performance in an elderly homebound patient following a total knee arthroplasty. Physiother Theory Pract. 2014 May;30(4):287-97. doi: 10.3109/09593985.2013.868064. Epub 2014 Jan 7.

    PMID: 24397371BACKGROUND
  • Wawrzyniak JR, Tracy JE, Catizone PV, Storrow RR. Effect of closed chain exercise on quadriceps femoris peak torque and functional performance. J Athl Train. 1996 Oct;31(4):335-40.

    PMID: 16558420BACKGROUND
  • Knight KL. Quadriceps Strengthening with the DAPRE Technique: Case studies with Neurological Implications. J Orthop Sports Phys Ther. 1990;12(2):66-71. doi: 10.2519/jospt.1990.12.2.66.

    PMID: 18787253BACKGROUND

MeSH Terms

Interventions

Conization

Intervention Hierarchy (Ancestors)

BiopsyCytodiagnosisCytological TechniquesClinical Laboratory TechniquesDiagnostic Techniques and ProceduresDiagnosisSpecimen HandlingDiagnostic Techniques, SurgicalSurgical Procedures, OperativeInvestigative Techniques

Study Officials

  • Rabiya Noor, PhD

    Riphah International University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 6, 2021

First Posted

March 10, 2021

Study Start

October 15, 2020

Primary Completion

May 20, 2021

Study Completion

May 20, 2021

Last Updated

September 2, 2021

Record last verified: 2021-08

Data Sharing

IPD Sharing
Will not share

Locations