The Impact of Eyelid Hygiene on Ocular Surface

NCT04789824 | Completed

• 1 other identifier: surgerynurse
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 2

Brief Summary

Dry eye is one of the most common eye diseases and it is known to be an ever-increasing public health problem in risky groups. Physical conditions (heat, light, humidity,ventilation), anesthetic gases, chemical-containing disinfectants and antiseptics are risk factors for dry eyes in operating rooms. In addition, the fact that surgery is a job that requires constant attention is considered among the factors that increase the risk of dry eye as it reduces the number of blinking. In the literature review, eye hygiene (hot application, massage, cleaning) is recommended as an application that protects and improves eye health. Because it has been reported to have significant positive effects on eye fatigue, dry eye symptoms and vision in both healthy and dry eyes. However, "daily eye hygiene" is a little-known practice in almost every society. In this context, the effect of eye hygiene on ocular surface moistening and vision-related quality of life in operating room workers was investigated in this study.The research was conducted as a randomized controlled experimental study between May 2018 and May 2019. All participants working in the operating room and meeting the inclusion criteria were included in the study. The group in which the participants will be included was determined by simple randomization. Eye hygiene training was given to the intervention group and eye hygiene practice was followed for 12 weeks. The control group was not intervened. Tear film stability and vision-related quality of life scores of both groups before and after 12 weeks of training were compared.

Conditions

Dry Eye

Keywords

dryeye; operation room; nurse; surgery; eyelid hygiene

Outcome Measures

Primary Outcomes (2)

• Stage ≥1 dry eye disease

  Volunteers with Tear Break-up Time \<10, Schirmer-1 test \<5, Oclar Surface Disease Index score ≥ 13, McMonnies Questionnaire\> 14.5 and reporting at least one severe ocular symptom (pain, stinging, burning, stinging, itching, dryness) were considered to be at least first stage dry eye.

  Weeks 0.-10.

• Visual Function

  Visual Function Questionnaire score 0-100

  Weeks 0.-10.

Study Arms (2)

Investigation group

EXPERIMENTAL

Eye Hygiene (warm compress, eyelid massage, and eyelid cleaning)

Behavioral: eyelid hygiene

Control Group

NO INTERVENTION

No intervention

Interventions

eyelid hygiene BEHAVIORAL

EH

Investigation group

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Actively working in the operating room setting, aged ≤50 years, and having Stage ≥1 dry eye disease. In a clinical examination by the ophthalmologist, volunteers with TBUT \<10, Schirmer test \<5, OSDI score ≥ 13, MQ score\> 14.5, cornea or conjunctiva\> 1 staining and reporting at least one severe ocular symptom

You may not qualify if:

• Active eye infection requiring treatment, receiving antihypertensives, antihistamines, psychogenic or chemotherapeutic agents, thyroid replacement therapy, or estrogen, having autoimmune diseases such as Sjögren's syndrome, rheumatoid arthritis, diabetes, or multiple sclerosis, having a previous anterior segment surgery, wearing contact lenses, receiving treatment for dry eye disease within the past six months, receiving omega-3 or vitamin A supplements currently or within the past three months, pregnant or lactating women, and menopausal or postmenopausal women

Sponsors & Collaborators

• Saglik Bilimleri Universitesi: lead

Study Sites (2)

Aslı Nemli

Kayseri, Talas, 35500, Turkey (Türkiye)

Location

Erciyes Universitesi Hastanesi

Kayseri, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Dry Eye Syndromes

Condition Hierarchy (Ancestors)

Lacrimal Apparatus Diseases; Eye Diseases

Study Officials

• Aslı Nemli, PhD

  Erciyes Üniversitesi

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: Single-blind, randomized-controlled

Study Record Dates

• First Submitted: February 25, 2021
• First Posted: March 10, 2021
• Study Start: June 1, 2018
• Primary Completion: June 1, 2019
• Study Completion: September 1, 2019
• Last Updated: March 10, 2021

Record last verified: 2021-03

Locations

TU (2)