NCT04789707

Brief Summary

Keratoconus is a progressive disorder in which central and paracentral corneal stromal thinning occurs. No studies evaluated the influence of keratoconus on stress at work, nor the influence of treatments of keratoconus on stress at work, including Quality of Life at work and on perception of work. Moreover, it has been shown that some pathologies had greater influence in some occupations, also depending on other characteristics of individuals such as age, sex or socio professional groups. Therefore, we hypothesized that keratoconus 1) will influence stress at work including QoL at work and perception of work, 2) will have a greater influence in some occupations and depending on age, sex, or stage of keratoconus, 3) will induce stoppage of work and occupational reclassifications.

Trial Health

57
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
22

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started May 2021

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 3, 2021

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 9, 2021

Completed
2 months until next milestone

Study Start

First participant enrolled

May 4, 2021

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 5, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 5, 2023

Completed
Last Updated

October 19, 2023

Status Verified

October 1, 2023

Enrollment Period

2 years

First QC Date

March 3, 2021

Last Update Submit

October 18, 2023

Conditions

Keywords

keratoconusKarasekstress at work

Outcome Measures

Primary Outcomes (1)

  • stress at work

    measured by Job Content questionnaire of Karasek

    day 0

Secondary Outcomes (7)

  • psychological consequences

    Day 0

  • Stoppage of work

    Day 0

  • Duration of stoppage of work

    Day 0

  • characteristics of the patient

    day 0

  • Measure of visual acuity.

    Day 0

  • +2 more secondary outcomes

Study Arms (2)

KERATOCONUS group

All workers with keratoconus all stages followed at the service of ophthalmology in CHU Gabriel Montpied, Clermont-Ferrand, Auvergne. The investigators only assessed data from usual routine practice. Patients answer the auto questionnaire in last minutes of consultation.

Behavioral: auto-questionnaire

CONTROL group

workers with good visual acuity consulting in ophthalmology service of Clermont-Ferrand. The investigators only assessed data from usual routine practice. Patients answer the auto questionnaire in last minutes of consultation.

Behavioral: auto-questionnaire

Interventions

Patients answer the auto questionnaire in last minutes of consultation.

CONTROL groupKERATOCONUS group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients with keratoconus patients constituting a representative control group of workers consulting in ophthalmology service of Clermont-Ferrand.

You may qualify if:

  • patients with keratoconus all stages followed at the CHU Gabriel Montpied,
  • patients constituting a representative control group of workers consulting in ophthalmology service of Clermont-Ferrand.

You may not qualify if:

  • an other ophtalmological disease alters visual acuity.
  • minors subjects
  • inability to provide informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU - Gabriel Montpied

Clermont-Ferrand, 63000, France

Location

MeSH Terms

Conditions

Keratoconus

Condition Hierarchy (Ancestors)

Corneal DiseasesEye Diseases

Study Officials

  • Frédéric DUTHEIL

    University Hospital, Clermont-Ferrand

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 3, 2021

First Posted

March 9, 2021

Study Start

May 4, 2021

Primary Completion

May 5, 2023

Study Completion

May 5, 2023

Last Updated

October 19, 2023

Record last verified: 2023-10

Locations