Use of the Modified PUQE Score on Admitted Cases of Hyperemesis Gravidarum (HG) to Guide Response to Treatment

NCT04785911 | Completed

• 1 other identifier: 17101318
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

Use of the PUQE score to judge the need for admission in cases of hyperemesis gravidarum Evaluation of the response to treatment by the PUQE score

Conditions

Hyperemesis Gravidarum

Keywords

PUQE score

Outcome Measures

Primary Outcomes (1)

• Detect improvement of patients by 1- daily scor of PUQE score 2-BMI by kg/m2 change from day of admission to day of discharge

  We can assess severity and change by daily score which detected by daily PUQE score and pre gestational BMI by kg/m2 and BMI by kg/m2 of pregenent women with hyperemisis from day of admission to hospital to day of discharge To descripe the PUQE score full text with scoring range will be attached Total score is sum of replies to each of the three questions. PUQE-24 score: Mild ≤ 6; Moderate = 7-12; Severe = 13-15. Motherisk PUQE-24 scoring system 1. the last 24 hours, for how long have you Felt nauseated or sick to your stomach? Not at all (1 ) 1hour or less (2) 2-3 hours(3) 4-6 hours (4) More than 6 hours (5) 2. In the last 24 hours have you vomited Or thrown up? 7 or more Times (5) 5-6 times (4) 3-4 times(3). 1-2 times(2) I did not throw up (1) 3. In the last 24 hours how many times Have you had retching or dry heaves Without bringing anything up? No time (1) 1-2 times(2) 3-4 times(3) 5-6 times (4) 7 or more times (5)

  Basline

Interventions

Antiemetic Combinations DRUG

Evaluation of response to treatment of hyperemisis gravidarum (antiemetics and other methods ) by PUQE score

Also known as: Steroids, Anti histamine

Eligibility Criteria

• Age: 16 Years - 46 Years
• Sex: female
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

All admitted pregenent cases complaining of hyperemisis gravidarum

You may qualify if:

• women hospitalized due to hyperemesis gravidarum with at least two out of three criteria; dehydration, weight loss \> 5% of prepregnancy weight (if known) or electrolyte imbalance/ketonuria.
• Gestational age between 6\_16 weeks.

You may not qualify if:

• Women Suffered from other diseases causing nausea and vomiting :
• gastritis
• renal diseases
• Hepatic disorders
• Throid disorders

Sponsors & Collaborators

• Tasnem Abo-elouon: lead
• Assiut University: collaborator

Study Sites (1)

Tasnem iIbrahem Aboelouon

Asyut, Assuit, 71684, Egypt

Location

Related Links

• Epidemiology of vomiting in early pregnancy.

MeSH Terms

Conditions

Hyperemesis Gravidarum

Interventions

Steroids; Histamine Antagonists

Condition Hierarchy (Ancestors)

Morning Sickness; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Vomiting; Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Fused-Ring Compounds; Polycyclic Compounds; Histamine Agents; Neurotransmitter Agents; Molecular Mechanisms of Pharmacological Action; Pharmacologic Actions; Chemical Actions and Uses; Physiological Effects of Drugs

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: January 21, 2021
• First Posted: March 8, 2021
• Study Start: September 5, 2021
• Primary Completion: October 1, 2022
• Study Completion: November 1, 2022
• Last Updated: April 5, 2023

Record last verified: 2023-04

Locations

EG (1)