Mean Platelet Volume and STEMI Clinical Risk Scores in Prediction of Impaired Myocardial Perfusion In Acute STEMI Patients Undergoing Primary Percutaneous Coronary Intervention.

NCT04785209 | Completed

• 1 other identifier: Prediction of No reflow
• Study Type: observational
• Target: 640
• Locations: 1 country
• Sites: 1

Brief Summary

Predicting no reflow in ppci of STEMI patients using mean platelet volume together with STEMI clinical risk scores

Conditions

No-Reflow Phenomenon

Outcome Measures

Primary Outcomes (1)

• Number of participents with No reflow after PPCI and in hospital mortality

  No reflow: suboptimal myocardial reperfusion through a part of coronary circulation without angiographic evidence of mechanical vessel obstruction. In hospital mortality

  Within 48 hours from admission

Study Arms (2)

No complication

Thrombolysis in myocardial infarction flow grade III flow after PPCI, mean platelet volume, lymphocyte ratio, detailed echo within 24 hrs of admission, clinical STEMI risk scores

Other: Mean platelet volume, lymphocyte number, STEMI clinical risk scores

No reflow

No reflow phenomenon after pci on STEMI patients, mean platelet volume, lymphocyte ratio, detailed echo within 24 hrs of admission, clinical STEMI risk scores

Other: Mean platelet volume, lymphocyte number, STEMI clinical risk scores

Interventions

Mean platelet volume, lymphocyte number, STEMI clinical risk scores OTHER

Lab parameters

No complication; No reflow

Eligibility Criteria

• Age: 16 Years+
• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All STEMI patients presenting within 24 hrs of onset of symptoms

You may qualify if:

• patients presenting with acute STEMI, within 24 hours of symptoms, fulfilling criteria for PPCI protocol in our facility

You may not qualify if:

• patients presenting more than 24 hours of symptoms onset
• patients not eligible for PPCI program in our facility

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut university hospital

Asyut, 71515, Egypt

Location

MeSH Terms

Conditions

No-Reflow Phenomenon

Interventions

Mean Platelet Volume; Lymphocyte Count

Condition Hierarchy (Ancestors)

Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Platelet Function Tests; Hematologic Tests; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Investigative Techniques; Cell Size; Cell Physiological Phenomena; Leukocyte Count; Blood Cell Count; Cell Count; Cytological Techniques; Blood Physiological Phenomena; Circulatory and Respiratory Physiological Phenomena

Study Officials

• Hamdy Shams elddin, Professor

  Assiut University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principle invistigator

Study Record Dates

• First Submitted: September 23, 2020
• First Posted: March 5, 2021
• Study Start: September 1, 2020
• Primary Completion: February 28, 2021
• Study Completion: May 1, 2024
• Last Updated: May 31, 2024

Record last verified: 2024-05

Locations

EG (1)