Evaluation of the Intra-observer Agreement of the HEP Score in Surgical Intensive Care.

NCT04782843 | Unknown

• 1 other identifier: 2021/586
• Study Type: observational
• Target: 124
• Locations: 0 countries
• Sites: N/A

Brief Summary

The main objective of this work is to assess the intraoperator reproducibility in the calculation of the HEP score in a population of intensive care patients.

Conditions

Heparin-induced Thrombocytopenia

Keywords

Heparin-induced Thrombocytopenia; HEP score

Outcome Measures

Primary Outcomes (1)

• Intraobserver agreeement for the HEP score

  Intraobserver agreeement for the HEP score

  3 months

Secondary Outcomes (1)

• Interobserver agreement for the HEP score

  3 months

Study Arms (1)

Cohort

he retrospective cohort studied includes all the patients included in a previous study carried out in our center, the objective of which was to study the diagnostic performance of the HEP score in surgical intensive care. The cohort studied is made up of all patients admitted for surgical resuscitation between October 2011 and October 2013 and validating the following criteria: * Inclusion criteria: any adult patient (age ≥ 18 years), admitted to surgical intensive care, treated with heparin (UFH or LMWH), and suspected of TIH by a clinician in the department according to the criteria of the SFAR 2002. * Non-inclusion criteria: minor patients, pregnant women and adults incapable.

Other: HEP score assessement

Interventions

HEP score assessement OTHER

Assessement of the HEP score between 2 physician.

Cohort

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The cohort studied is made up of all patients admitted for surgical resuscitation between October 2011 and October 2013

You may qualify if:

• any adult patient (age ≥ 18 years), admitted to surgical intensive care, treated with heparin (UFH or LMWH), and suspected of TIH by a clinician in the department according to the criteria of the SFAR 2002.

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Besancon: lead

Related Publications (1)

• Cuker A, Arepally G, Crowther MA, Rice L, Datko F, Hook K, Propert KJ, Kuter DJ, Ortel TL, Konkle BA, Cines DB. The HIT Expert Probability (HEP) Score: a novel pre-test probability model for heparin-induced thrombocytopenia based on broad expert opinion. J Thromb Haemost. 2010 Dec;8(12):2642-50. doi: 10.1111/j.1538-7836.2010.04059.x.

  PMID: 20854372 RESULT

Related Links

• Princeps article

Study Officials

• Guillaume Besch, MD

  CHRU J. Minjoz à Besançon

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Rudy Alardin, Intern

CONTACT

0621605385; ralardin@chu-besancon.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 2, 2021
• First Posted: March 4, 2021
• Study Start: March 1, 2021
• Primary Completion: May 1, 2021
• Study Completion: May 1, 2021
• Last Updated: March 4, 2021

Record last verified: 2021-02

Data Sharing

• IPD Sharing: Will not share