NCT04771195

Brief Summary

The central goal of this project is to produce a novel, precise, and comprehensive account of social factors in young adult mental health - using a novel combination of network nominations, ecological momentary assessment, and neuroimaging methods. To that end, the investigators will collect data from two successive classes of college undergraduates (i.e., classes of 2023 and 2024) over the course of their collegiate tenure.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
9,941

participants targeted

Target at P75+ for not_applicable anxiety

Timeline
Completed

Started Aug 2021

Longer than P75 for not_applicable anxiety

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 22, 2021

Completed
3 days until next milestone

First Posted

Study publicly available on registry

February 25, 2021

Completed
6 months until next milestone

Study Start

First participant enrolled

August 30, 2021

Completed
4.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 8, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 8, 2026

Completed
Last Updated

June 1, 2026

Status Verified

May 1, 2026

Enrollment Period

4.7 years

First QC Date

February 22, 2021

Last Update Submit

May 28, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Depression

    Score on self-reported depression measure: Center for Epidemiological Studies Scale - 10 item version. Range = 0 to 30. Higher scores indicate more depressive symptoms

    September 2021 - May 2024

  • Anxiety

    Score on self-reported anxiety measure: State-Trait Anxiety Inventory - 20 item version. Range = 20 to 80. Higher scores indicate more symptoms of anxiety.

    September 2021 - May 2024

Secondary Outcomes (2)

  • Loneliness

    September 2021 - May 2024

  • Stress

    September 2021 - May 2024

Study Arms (1)

Class of 2023 and 2024

EXPERIMENTAL

Stanford undergraduate students who are expected to graduate in Spring of 2023 or 2024

Behavioral: Examination of students' naturally occurring social ties

Interventions

In this observational study, features of students' social lives, such as the number of quality of relationships they form, and their subjective loneliness, will be used to predict their mental health and well being at later time points.

Class of 2023 and 2024

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Stanford University

Stanford, California, 94305, United States

Location

MeSH Terms

Conditions

Anxiety DisordersDepression

Condition Hierarchy (Ancestors)

Mental DisordersBehavioral SymptomsBehavior

Study Officials

  • Jamil Zaki, PhD

    Stanford University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

February 22, 2021

First Posted

February 25, 2021

Study Start

August 30, 2021

Primary Completion

May 8, 2026

Study Completion

May 8, 2026

Last Updated

June 1, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will share

Unidentifiable data will be shared with other researchers. To that end, alphanumeric identifiers will be assigned to each individual in the sample's population. Direct nomination lists will not be shared because the potential traceability for participants who may gain access to the data after it is published.

Shared Documents
STUDY PROTOCOL, SAP, ANALYTIC CODE

Locations