NCT04766801

Brief Summary

Obesity affects 3%-4% of the pediatric population and leads to cardiac mortality during adult life. Bariatric surgery is the best treatment for weight loss and preventing obesity associated comorbidities in adults, but its applications and safety are yet to be defined for adolescents.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
57mo left

Started Jan 2008

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress80%
Jan 2008Dec 2030

Study Start

First participant enrolled

January 1, 2008

Completed
12.9 years until next milestone

First Submitted

Initial submission to the registry

November 27, 2020

Completed
3 months until next milestone

First Posted

Study publicly available on registry

February 23, 2021

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2021

Completed
9.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2030

Expected
Last Updated

February 23, 2021

Status Verified

February 1, 2021

Enrollment Period

13.8 years

First QC Date

November 27, 2020

Last Update Submit

February 19, 2021

Conditions

Keywords

gastric bandingcomplicationsweight loss

Outcome Measures

Primary Outcomes (1)

  • Change of weight parameters at 2 years compared to preoperative baseline

    Evaluation of weight loss by weight (Kg), body mass index (BMI, Kg.m-2) and excess body weight (EBWL, %) changes

    2 years

Secondary Outcomes (8)

  • Changes of insulin resistance at 2 years

    2 years

  • Evaluation of dyslipidemia

    2 years

  • Evaluation of liver steatosis

    2 years

  • Resolution of comorbidities associated with obesity

    2 years

  • Monitoring of psychiatric profile

    2 years

  • +3 more secondary outcomes

Interventions

Weight-loss surgery, with the use of gastric banding

Eligibility Criteria

Age14 Years - 20 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Pediatric patients treated in our hospital for morbid obesity (BMI \>= 35 Kg.M-2) through different programs with lifestyle and nutritional interventions and, for those who requested it, the possibility of bariatric surgery.

You may qualify if:

  • Patients aged 14-20 years of age and asking for bariatric surgery
  • BMI \>= 40 Kg.m-2 or \>= 35 Kg.m-2 with major obesity-related comorbidities (hypertension, diabetes, sleep apnea, etc...)

You may not qualify if:

  • An unstable psychiatric disorder
  • Bariatric surgery anesthesic contraindications
  • Having not completed a minimum of six months of the pre operative program
  • Lack of consent from the patient or the patient's relatives.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital of Angers

Angers, Maine Et Loire, 49933, France

RECRUITING

MeSH Terms

Conditions

Obesity, MorbidPediatric ObesityWeight Loss

Condition Hierarchy (Ancestors)

ObesityOverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsBody Weight Changes

Study Officials

  • Françoise Schmitt, MD-PhD

    University Hospital of Angers

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Françoise Schmitt, MD-PhD

CONTACT

Régis Coutant, MD-PhD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 27, 2020

First Posted

February 23, 2021

Study Start

January 1, 2008

Primary Completion

October 31, 2021

Study Completion (Estimated)

December 31, 2030

Last Updated

February 23, 2021

Record last verified: 2021-02

Locations