Short- Term Follow up Of Neonates Born With Neural Tube Defect

NCT04760509 | Unknown

• 1 other identifier: GO201150
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

Neural tube defects (NTD), which is the most common anomaly of the central nervous system, which can be diagnosed during antenatal period, brings many problems both in the neonatal period and in advanced ages. Open neural tube defects, in particular, progress with sensory-motor deficits due to the risk of infection and neural tissue loss from birth, and should be followed closely from the neonatal period. Newborns born with a neural tube defect should be operated within the first 72 hours postnatal and the defect should be closed. In this hospital, newborns with NTD are monitored in our neonatal surgery intensive care unit before and after surgery. Neonatal specialists, neurosurgeons and other specialists when there is an additional anomaly evaluate the baby as multidisciplinary. In this project, the short-term follow-up data of babies with NTD who have been followed up in this neonatal surgery intensive care unit for the last fifteen years will be evaluated retrospectively.

Conditions

Neural Tube Defects; Newborn Morbidity

Keywords

newborn; neural tube defects; meningomyelosel

Outcome Measures

Primary Outcomes (1)

• the day of surgery to be performed in the postnatal period

  It is aimed to demonstrate the effects of early or late surgery day on the baby in the postnatal period.

  8 months

Interventions

In this study, the short-term follow-up of patients with neural tube defects in the neonatal intensive care unit will be evaluated retrospectively. OTHER

there is no intervention. It is retrospective study.

Also known as: meningomyelosel

Eligibility Criteria

• Age: 0 Days - 28 Days
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

The method and data collection tools of the study: the information of the patients hospitalized in the neonatal intensive care unit with a diagnosis of neural tube defect between January 1, 2006 and January 1, 2021 will be recorded in the file. In addition to demographic information such as antenatal follow-up data, maternal diseases, birth weights, birth weeks, delivery types of patients, neurological examinations, laboratory findings, imaging (such as graphy, tomography, ultrasonography), surgery during the follow-up in our unit.

You may qualify if:

• Babies who have been hospitalized in the Neonatal Intensive Care Unit of Hacettepe University İhsan Dogramaci Children's Hospital and who have been operated due to neural tube defects will be taken.

You may not qualify if:

• Patients whose file records cannot be reached will not be included.

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Umit Ayse Tandircioglu

Ankara, 06230, Turkey (Türkiye)

Location

Related Publications (2)

• Richard J. Martin, MBBS, FRACP, Avroy A. Fanaroff, MD, FRCPE, FRCPCH, Michele C. Walsh, MD, MSE Fanaroff and Martin's Neonatal-Perinatal Medicine. Diseases of the Fetus and Infant. 11th Edition 1073- 1080.

  BACKGROUND

• McLone DG. Care of the neonate with a myelomeningocele. Neurosurg Clin N Am. 1998 Jan;9(1):111-20.

  PMID: 9405769 RESULT

MeSH Terms

Conditions

Neural Tube Defects

Condition Hierarchy (Ancestors)

Nervous System Malformations; Nervous System Diseases; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Medical Doctor

Study Record Dates

• First Submitted: February 15, 2021
• First Posted: February 18, 2021
• Study Start: February 1, 2021
• Primary Completion: September 30, 2021
• Study Completion: December 31, 2021
• Last Updated: February 18, 2021

Record last verified: 2021-02

Locations

TU (1)