NCT04760054

Brief Summary

The investigators' study is designed to test whether brief exposure to a martial arts-based intervention (a coordinative, partnered training exercise known as "Hubod"), can improve cognitive function to a greater degree than aerobic exercise of a similar intensity.

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
32

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2021

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 15, 2021

Completed
3 days until next milestone

First Posted

Study publicly available on registry

February 18, 2021

Completed
1 month until next milestone

Study Start

First participant enrolled

March 24, 2021

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 15, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 15, 2021

Completed
Last Updated

August 25, 2022

Status Verified

August 1, 2022

Enrollment Period

9 months

First QC Date

February 15, 2021

Last Update Submit

August 22, 2022

Conditions

Keywords

Cognitive PerformanceComplex movement

Outcome Measures

Primary Outcomes (2)

  • Digit Symbol Substitution task

    Processing speed and working memory cognitive task using numbers and symbols. Participants will be presented with multiple rows of symbols, each one corresponding to a number on a 1-9 scale and they will have two minutes to correctly match (in sequential order) as many symbols to their numbers as possible. Performance is computed by adding the number of symbols correctly-matched within the allotted time.

    Participants will be assessed at baseline and in the week immediately following the two-week intervention period.

  • n-2back memory task

    Working memory cognitive task involving a sequence of shapes briefly appearing on a computer screen. If the shape on screen is identical to the shape two stages before, the participant will press the 'match' key. If they are not identical, the participant should do nothing. Performance is derived by the number of correctly-matched shapes in the sequence and calculating the average reaction time across the trials.

    Participants will be assessed at baseline and in the week immediately following the two-week intervention period.

Secondary Outcomes (3)

  • Matrix Reasoning Task

    Participants will be assessed at baseline and in the week immediately following the two-week intervention period.

  • Trail-Making Test

    Participants will be assessed at baseline and in the week immediately following the two-week intervention period.

  • Flanker Task

    Participants will be assessed at baseline and in the week immediately following the two-week intervention period.

Other Outcomes (14)

  • Perceived Mental Fatigue Questionnaire

    Participants will be assessed at baseline and in the week immediately following the two-week intervention period; also delivered immediately prior to and following each of the five intervention training sessions.

  • Grip strength task

    Participants will be assessed at baseline and in the week immediately following the two-week intervention period.

  • Stair-climb task

    Participants will be assessed at baseline and in the week immediately following the two-week intervention period.

  • +11 more other outcomes

Study Arms (3)

HUBOD martial arts practice

EXPERIMENTAL

Participants will be trained in the Hubod exercise over 5 separate training sessions. Sessions will last approximately 30 minutes, involving a warm up, review of material from the previous session and the learning of the next movement in the HUBOD sequence. Heartrate will be monitored periodically to make sure the intensity of exercise is consistent with mild to moderate cardiovascular exercise as in the active comparator.

Behavioral: HUBOD

Active Comparator - Stationary Bicycle

ACTIVE COMPARATOR

Participants will be given 5 separate sessions, each approximating 30 minutes in duration, of mild to moderate intensity cardiovascular training on a stationary bicycle. Heartrate will be monitored periodically to make sure the intensity of exercise is consistent with mild to moderate exercise as in the Experimental group.

Behavioral: Active Comparator

Attentional Control Group

PLACEBO COMPARATOR

Participants will be given 5 separate sessions, each approximating 30 minutes in duration, of watching videos on martial arts training methods and techniques. These sessions will be completely sedentary.

Behavioral: Control Condition

Interventions

HUBODBEHAVIORAL

Participants in the intervention group will attend 5 separate training sessions instructing them in Hubod. The Hubod exercise is a partnered coordination drill involving moves derived from numerous martial arts, most often seen in the Filipino martial art of Kali. Participants will aim to reach a level of comfort and competency in the basic, non-competitive aspects of the Hubod exercise by the end of their participation in this intervention.

Also known as: Martial Arts Experimental Exercise Group, Hubod Training Group
HUBOD martial arts practice

Participants in the active comparator group will attend 5 separate training sessions. Each session will involve a 5 minute warmup of joint mobilization exercises and mild pedaling on the bicycle before the main effort of continuously using the bicycle for approximately 20 minutes. The session finishes with a 5 minute cooldown period and light stretch. Heartrate will be monitored regularly in order to prevent this exercise exceeding the relative intensity of the Martial Arts intervention group. Participants will be allowed to talk and interact with research assistants in order to keep socialization effects consistent across groups.

Also known as: Exercise Comparison Group, Stationary Bike Group
Active Comparator - Stationary Bicycle

Participants in this group will attend 5 separate training sessions. Each session will involve watching educational videos on martial arts techniques and training methods from a sedentary position. Participants will be allowed to talk and interact with research assistants in order to keep socialization effects consistent across groups.

Attentional Control Group

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • \- Men and Women between the ages of 18-45 years who are low active

You may not qualify if:

  • Anyone who is physically active (≥30 minutes, 3 or more times/week, for the last 3 months) and/or a regular practitioner of martial arts and/or highly complex coordination drills such as dance performance or contact improvisation (≥30 minutes, 3 or more times/week, for the last 3 months).
  • Anyone with serious chronic medical conditions that would preclude them from participating without a physician present, or anyone with a risk of seizure, or anyone having psychiatric and/or neurological disorders.
  • Pregnant women.
  • Anyone incapable of performing the following movements at a moderate intensity- sitting, standing, kicking, pulling, pushing, bending one's elbows or bending one's knees.
  • Anyone who scores 1 or more on the Physical Activity Readiness Questionnaire
  • Anyone refusing or unwilling to be randomized into either of the conditions.
  • Anyone who cannot commit to both 45 minute testing sessions or the five 30-minute training sessions.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Exercise, Technology, and Cognition Laboratory - Louise Freer Hall 284

Urbana, Illinois, 61801, United States

Location

MeSH Terms

Conditions

Spatial ProcessingInhibition, Psychological

Condition Hierarchy (Ancestors)

Spatial BehaviorBehavior

Study Officials

  • Sean P Mullen, PhD

    University of Illinois at Urbana-Champaign

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
The outcomes assessor will be masked to group allocation. Participants will not be masked from knowledge of other group's activities, but will only receive the training from one specific training group.
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: Three groups: One intervention, One Exercise Comparison, One Attentional Control
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor Sean Mullen

Study Record Dates

First Submitted

February 15, 2021

First Posted

February 18, 2021

Study Start

March 24, 2021

Primary Completion

December 15, 2021

Study Completion

December 15, 2021

Last Updated

August 25, 2022

Record last verified: 2022-08

Data Sharing

IPD Sharing
Will not share

IPD will only be available to the Primary investigator and Lead research assistant of this study.

Locations