Effects of Short- Term Intermittent Fasting Aerobic and Anaerobic Capacity

NCT04756635 | Unknown

• 1 other identifier: joana_correia
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The therapeutic use of caloric restriction and intermittent fasting (IF) protocols improves life span and health related quality of life. The effects of fasting protocols on athletic performance and training adaptations have been primarily studied in athletes undergoing the Ramadan IF protocol or in athletes willing to decrease body fat, while maintaining or increasing lean body mass. Data from these studies are somewhat conflicting and unclear. Moreover, the effects of IF on muscular strength, as well as in aerobic and anaerobic capacity remain largely unknown. Anecdotal evidence from experienced participants in strength, power and endurance training or sports, indicates an increased ability to acutely display higher levels of work capacity in the fasted vs. fed state. The goal of this project is to determine the effects of 4 wks of IF on neuromuscular performance, aerobic and anaerobic capacity of well-trained young adults.

Conditions

Healthy Males; Men

Keywords

Intermittent fasting; neuromuscular performance; aerobic capacity; anaerobic capacity

Outcome Measures

Primary Outcomes (1)

• Change from Baseline Performance at 4 weeks

  Neuromuscular performance, aerobic and anaerobic capacity

  4weeks (experiemental) + 4weeks (control)

Secondary Outcomes (1)

• Change from Baseline Body Composition at 4 weeks

  4weeks (experiemental) + 4weeks (control)

Study Arms (2)

Experimental Group

EXPERIMENTAL

Measures taken before and after the defined IF periods. Two groups of participants will be included in this project: 1) resistance trained group (tested for neuromuscular function, anaerobic capacity and body composition); 2) endurance trained group (tested for aerobic and anaerobic capacity and body composition). Experimental condition: pre- and post-4 weeks of IF. Measurements will be taken during the morning period (between 07:00 and 11:00 am) in the fasted state. Neuromuscular function and anaerobic capacity will be assessed on separate days (with at least a 48- hour interval) to ensure full recovery.

Other: Experimental Group

Control Group

OTHER

Participants of each group serving as their own controls. Control condition: pre- and post4 weeks of normal diet. Measurements will be taken during the morning period (between 07:00 and 11:00 am) in the fasted state. Neuromuscular function and anaerobic capacity will be assessed on separate days (with at least a 48-hour interval) to ensure full recovery.

Other: Experimental Group

Interventions

Experimental Group OTHER

This 3-year project will include two groups of participants: 1) young men accustomed to resistance training (study #1) and 2) young men accustomed to endurance training (study #2). Inclusion will be limited to healthy participants (i.e. nonsmokers, normotensive with systolic and diastolic values \<135/85 mmHg, non-obese, non-medicated, and free of any known disease as assessed by medical history) (Pickering, Hall et al. 2005). Month 1-3 will focus on literature review and month 4 to 8 will address experimental settings preparation and selection of participants to include in each study. Testing and data collection will be scheduled for months 9-14 and 13-18 (study # 1 and 2 related testing, respectively). Data processing, analysis and presentation will occur from month 21 to 33. All participants will read and sign an informed consent document with the description of the testing procedures. The Faculty's ethical committee will be asked to approve this document before testing.

Also known as: Aerobic capacity, Anaerobic capacity, Neuromuscular performance

Control Group; Experimental Group

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

Sponsors & Collaborators

• Faculdade de Motricidade Humana: lead

Study Sites (1)

Joana Correia

Lisbon, 1499-002, Portugal

RECRUITING

Related Publications (1)

• Correia JM, Pezarat-Correia P, Minderico C, Infante J, Mendonca GV. Effects of Time-Restricted Eating on Aerobic Capacity, Body Composition, and Markers of Metabolic Health in Healthy Male Recreational Runners: A Randomized Crossover Trial. J Acad Nutr Diet. 2024 Aug;124(8):1041-1050. doi: 10.1016/j.jand.2024.01.005. Epub 2024 Jan 17.

  PMID: 38242204 DERIVED

MeSH Terms

Conditions

Multiple Endocrine Neoplasia Type 1; Intermittent Fasting

Condition Hierarchy (Ancestors)

Multiple Endocrine Neoplasia; Endocrine Gland Neoplasms; Neoplasms by Site; Neoplasms; Neoplasms, Multiple Primary; Neoplastic Syndromes, Hereditary; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases; Fasting; Feeding Behavior; Behavior

Study Officials

• Joana M. Correia, Master

  Faculdade de Motricidade Humana

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Joana M. Correia, Master

CONTACT

911197842; joanacorreia-19@live.com.pt

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: February 12, 2021
• First Posted: February 16, 2021
• Study Start: May 22, 2018
• Primary Completion: April 12, 2021
• Study Completion: February 5, 2023
• Last Updated: July 26, 2022

Record last verified: 2022-07

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, CSR
• Time Frame: The data will be stored in an SPSS and excel database, on the server of the Faculty of Human Motricity assigned to the Motor Behavior Laboratory. Paper-based documents will be destroyed after the data processing matrix is built.
• Access Criteria: Public articles with no reference to participants

Locations

PT (1)