Exploring Breathing Patterns

NCT04754490 | Suspended

• 1 other identifier: 256266
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Study Title Exploring patterns of speech and breathing to indicate the presence of obstructive respiratory disease. Study Design Prospective Case Control Study Study Participants Participants will be patients attending the respiratory physiology clinic at the Cardiopulmonary Unit, Prince Charles Hospital for an assessment of their lung function. In addition a cohort of control participants without obstructive respiratory disease will be recruited with the assistance of the British Lung Foundation charity. Planned Size of Sample (if applicable) We have received funding for 52 ½ day sessions and we plan to recruit on average 2 participants per session. As such we aim to recruit a minimum of 100 participants. In addition we are working with the British Lung Foundation to recruit a smaller Cohort of control participants and aim to recruit a minimum of 25 control participants. Planned Study Period Jan 2019 - Aug 2019 Research Aim(s) This primary objective of this novel study it to create an anonymised database of speech patterns of patients with chronic respiratory disease and healthy aged matched controls for comparison with lung function and medical history. The primary aims are to:

• Collect breathing patterns from individuals under a range of talking modalities
• Understand how easy it is to gather short speech recordings
• Explore the preferences of patients to be recorded talking

Conditions

COPD

Outcome Measures

Primary Outcomes (3)

• Collect breathing patterns from individuals under a range of talking modalities

  breathing pattern

  less than 5 minutes

• Understand how easy it is to gather short speech recordings

  verbal description

  3 minutes

• Explore the preferences of patients to be recorded talking

  verbal description

  3 minutes

Interventions

Speech Recognition DIAGNOSTIC_TEST

Speech Recognition

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patient \>18 years old referred for spirometry in the Respiratory Physiology Clinic at Prince Charles Hospital; Eligibility Criteria - Control Participants Control participants will be contact through the British Lung Foundations local groups who have indicated their willingness to be involved in local clinical research to act as control participants. As all prospective participants will have had their respiratory function measured before taking part by a Respiratory Physiologist, we do not expect to have to screen for medical issues for participation in the study. Furthermore, the actual tests the participants will be undertaking will be non - invasive, submaximal and will require little or no effort.

You may qualify if:

• Adult patient \>18 years old referred for spirometry in the Respiratory Physiology Clinic at Prince Charles Hospital;
• Clinically defined obstructive or restrictive respiratory disease (indicated by spirometry)
• Clinically stable (indicated by being able to undergo spirometry)
• No significant unstable disease co-morbidities (indicated by being able to undergo spirometry)
• Capable of providing informed consent.
• Willing to take part in all study measurements.
• The speaking exercise will be conducted in English on this study.
• \. No obstructive or restrictive respiratory disease (indicated by spirometry) 2. Clinically stable (indicated by being able to undergo spirometry) 3. No significant unstable disease co-morbidity's (indicated by being able to undergo spirometry) 4. Capable of providing informed consent. 5. Willing to take part in all study measurements. 6. The speaking exercise will be conducted in English on this study. 7. Participants are not taking part in any other research.

You may not qualify if:

• Any form of challenge testing in the Respiratory Physiology Department involving salbutamol.
• Severe Sensory and/or Cognitive Impairment
• Inability to complete study measurements

Sponsors & Collaborators

• Cwm Taf University Health Board (NHS): lead

Study Sites (1)

Cwm Taf Morgannwg Health Board

Abercynon, Wales, CF45 4SN, United Kingdom

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 10, 2021
• First Posted: February 15, 2021
• Study Start: March 1, 2019
• Primary Completion: March 1, 2022
• Study Completion: March 1, 2022
• Last Updated: February 15, 2021

Record last verified: 2021-02

Data Sharing

• IPD Sharing: Will not share

Locations

GB (1)