NCT04750187

Brief Summary

The purpose of this study will be to assess the effects of an 8-week hypo-pressive abdominal exercise program on Inspiratory muscle strength, diaphragm thickness, pressure pain threshold and disability in patients with non-specific chronic low back pain. A randomized clinical trial will be carried out. A total sample of 40 patients with non-specific chronic low back pain will be recruited and divided into 2 groups including an experimental group (n=20) which will receive an 8-week hypo-pressive abdominal exercise program and a control group (n=20) which will not receive any training program. Inspiratory muscle strength, diaphragm thickness, pressure pain threshold and disability will be assessed.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable low-back-pain

Timeline
Completed

Started Feb 2021

Shorter than P25 for not_applicable low-back-pain

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 7, 2021

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 11, 2021

Completed
4 days until next milestone

Study Start

First participant enrolled

February 15, 2021

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 15, 2021

Completed
3 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 18, 2021

Completed
Last Updated

May 19, 2021

Status Verified

May 1, 2021

Enrollment Period

3 months

First QC Date

February 7, 2021

Last Update Submit

May 18, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Inspiratory muscle strength

    Inspiratory muscle strength will be measured in % by a POWER-breathe device

    Change from baseline inspiratory muscle strength at 8 weeks

Secondary Outcomes (3)

  • Diaphragm muscle thickness

    Change from baseline diaphragm muscle thickness at 8 weeks

  • Pressure pain threshold

    Change from baseline pressure pain threshold at 8 weeks

  • Disability

    Change from baseline disability at 8 weeks

Study Arms (2)

Hypo-pressive abdominal exercise program

EXPERIMENTAL
Other: Hypo-pressive abdominal exercise intervention

No training program

NO INTERVENTION

Interventions

An 8-week hypo-pressive abdominal exercise program

Hypo-pressive abdominal exercise program

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with chronic non-specific low back pain

You may not qualify if:

  • Congenital diseases
  • Rheumatic or neuro-muscular diseases
  • Respiratory conditions
  • Surgery
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universidad Francisco de Vitoria

Pozuelo de Alarcón, Madrid, 28223, Spain

Location

Related Publications (1)

  • Calvo-Lobo C, Almazan-Polo J, Becerro-de-Bengoa-Vallejo R, Losa-Iglesias ME, Palomo-Lopez P, Rodriguez-Sanz D, Lopez-Lopez D. Ultrasonography comparison of diaphragm thickness and excursion between athletes with and without lumbopelvic pain. Phys Ther Sport. 2019 May;37:128-137. doi: 10.1016/j.ptsp.2019.03.015. Epub 2019 Mar 28.

    PMID: 30954705BACKGROUND

MeSH Terms

Conditions

Low Back Pain

Condition Hierarchy (Ancestors)

Back PainPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

February 7, 2021

First Posted

February 11, 2021

Study Start

February 15, 2021

Primary Completion

May 15, 2021

Study Completion

May 18, 2021

Last Updated

May 19, 2021

Record last verified: 2021-05

Locations