NCT04749134

Brief Summary

Non-patient volunteers will be scanned on the MR-Linac and MRSIM to facilitate the development, optimisation and validation of MRI protocols at The Christie NHS Foundation Trust.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
28mo left

Started Aug 2021

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress67%
Aug 2021Aug 2028

First Submitted

Initial submission to the registry

January 27, 2021

Completed
15 days until next milestone

First Posted

Study publicly available on registry

February 11, 2021

Completed
6 months until next milestone

Study Start

First participant enrolled

August 1, 2021

Completed
7.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2028

Last Updated

August 24, 2025

Status Verified

August 1, 2025

Enrollment Period

7.1 years

First QC Date

January 27, 2021

Last Update Submit

August 19, 2025

Conditions

Focus of the Study is MRI Sequence Development

Outcome Measures

Primary Outcomes (1)

  • Developed and optimised of MRI scanning sequences for use in clinical radiotherapy practice in MR guided radiotherapy

    on-going development of MRI protocols to be released for clinical use

    Through study completion - up to 5 years

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Personnel at The Christie NHS Foundation Trust

You may qualify if:

  • Willing and able to provide written consent
  • Volunteers must undergo and satisfy MRI safety screening
  • Volunteers must be ≥ 16 years of age
  • Participants must agree to registration as a non-patient in CWP (the Trust's Electronic Health Record - EHR- system) and have their MRIs read and reported for incidental findings by a clinical radiologist

You may not qualify if:

  • Any contraindications to MRI identified after MRI safety screening including completion of an MRI Safety Screening Form
  • Unable to tolerate MRI scan
  • Known Pregnancy
  • Known or suspected pathology in body region to be scanned
  • Member of study team

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Christie NHS FT

Manchester, United Kingdom

RECRUITING

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Head of Radiotherapy Research and Development

Study Record Dates

First Submitted

January 27, 2021

First Posted

February 11, 2021

Study Start

August 1, 2021

Primary Completion (Estimated)

August 31, 2028

Study Completion (Estimated)

August 31, 2028

Last Updated

August 24, 2025

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will not share

Locations

GB(1)