Follow up Patients With Thoracolumbar Spondylodiscitis Surgically Treated by Posterior Approach

NCT04749082 | Unknown

• 1 other identifier: spondylodiscitis surgery
• Study Type: observational
• Target: 40
• Locations: 0 countries
• Sites: N/A

Brief Summary

To evaluate the long term outcomes of patients with thoracolumbar spondylodiscitis treated surgically by posterior approach. Outcomes include bony fusion, neurological improvement, pain improvement, implant related complication, recurrence of infection and or reoperation rate

Conditions

Spondylodiscitis

Keywords

discitis; Spondylitis; Spine surgery

Outcome Measures

Primary Outcomes (1)

• Bony fusion success

  the degree of bridging bone across the fused vertebral bodies by using x-ray, CT scan and MRI if needed

  2 years

Secondary Outcomes (3)

• modified Oswestry disability index

  2 years

• visual analogue scale

  2years

• American spinal injury Association (ASIA) Impairment score

  2 years

Eligibility Criteria

• Age: 20 Years - 85 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All Patients suffered from thoracolumbar spondylodiscitis and treated surgically by posterior approach in Assiut university hospitals from January 2016 to December 2017

You may qualify if:

• All patients had thoracolumbar spondylodiscitis from number 1 thoracic vertebra till number 1 sacral vertebra.
• Treated surgically by posterior approach only.

You may not qualify if:

• Patients with incomplete follow up.
• Multifocal discitis.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (3)

• Kamal AM, El-Sharkawi MM, El-Sabrout M, Hassan MG. Spondylodiscitis: experience of surgical management of complicated cases after failed antibiotic treatment. SICOT J. 2020;6:5. doi: 10.1051/sicotj/2020002. Epub 2020 Feb 14.

  PMID: 32057290 BACKGROUND

• Berbari EF, Kanj SS, Kowalski TJ, Darouiche RO, Widmer AF, Schmitt SK, Hendershot EF, Holtom PD, Huddleston PM 3rd, Petermann GW, Osmon DR, Infectious Diseases Society of America. 2015 Infectious Diseases Society of America (IDSA) Clinical Practice Guidelines for the Diagnosis and Treatment of Native Vertebral Osteomyelitis in Adults. Clin Infect Dis. 2015 Sep 15;61(6):e26-46. doi: 10.1093/cid/civ482. Epub 2015 Jul 29.

  PMID: 26229122 BACKGROUND

• El-Sharkawi MM, Said GZ. Instrumented circumferential fusion for tuberculosis of the dorso-lumbar spine. A single or double stage procedure? Int Orthop. 2012 Feb;36(2):315-24. doi: 10.1007/s00264-011-1401-9. Epub 2011 Nov 10.

  PMID: 22072401 BACKGROUND

MeSH Terms

Conditions

Discitis; Spondylitis

Condition Hierarchy (Ancestors)

Bone Diseases, Infectious; Infections; Bone Diseases; Musculoskeletal Diseases; Spinal Diseases

Study Officials

• Essam M Abdelmoneim Elmorshidy, Lecturer

  Assiut University

  PRINCIPAL INVESTIGATOR

• El Moataz A Zohny El Sabrout, professor

  Assiut University

  STUDY CHAIR

• Belal O Mohamed Elnady, Lecturer

  Assiut University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Micheal B Elia, resident

CONTACT

01282682989; mikelbassem@hotmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: January 5, 2021
• First Posted: February 10, 2021
• Study Start: January 31, 2021
• Primary Completion: June 30, 2021
• Study Completion: July 1, 2021
• Last Updated: February 10, 2021

Record last verified: 2021-02