Task of Acoustic-phonetic Decoding on Anatomic Deficits in Paramedical Assessment of Speech Disorders for Patients Treated for Oral or Oropharyngeal Cancer

NCT04742998 | Unknown

• 2 other identifiers: RC31/20/05512020-A02335-34
• Study Type: observational
• Target: 116
• Locations: 1 country
• Sites: 3

Brief Summary

The bridging of the gap between speech production and perception by the interlocutor would be made possible by the use of a more suitable and automatic task. An acoustic-phonetic decoding test (or DAP in French, i.e. the production of isolated pseudo-words in repetition or reading), created within the framework of the The French National Cancer Institute (InCA) C2SI project, avoids the effects of cognitive restoration by the interlocutor. An automatic score from the DAP would lead to an overall score per patient, but also to scores specific to each phonetic segment, to be correlated with the analytical scores from each anatomical oropharyngeal segment. The study hypothesis is that the automatic processing of an acoustic-phonetic decoding task during the assessment in current practice is a valid and reliable tool for diagnosing oropharyngeal analytical and dynamic deficits by highlighting deficient linguistic units. The study hypothesis is that the automatic processing of an acoustico-phonetic decoding task during the assessment in current practice is a tool for diagnosing oropharyngeal analytical and dynamic deficits by highlighting deficient linguistic units.

Conditions

Speech Intelligibility

Keywords

speech deficit; tumor pathologies of the upper aero-digestive tract

Outcome Measures

Primary Outcomes (1)

• Correlation coefficient

  Correlation coefficient between he automatic score by phoneme class from the DAP and the score for each oropharyngeal anatomical segment from muscle testing

  Day 1

Secondary Outcomes (3)

• Human perceptual score - Direct transcription

  Day 1

• Human perceptual score - jury transcription

  Day 1

• Head and Neck Carcinologic Handicap Index (HNCHI)

  Day 1

Study Arms (1)

Patients treated for an oral or oropharyngeal tumor for at least 6 months

Patients treated for an oral or oropharyngeal tumor for at least 6 months

Other: Acoustic-phonetic decoding task (DAP)

Interventions

Acoustic-phonetic decoding task (DAP) OTHER

Completion of speech-related quality of life autoquestionnaires Routine speech assessment Acoustic-phonetic decoding task (DAP) two lists of 16 pseudo-words

Patients treated for an oral or oropharyngeal tumor for at least 6 months

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All site have an active group of person allowing a feasibility of recruitment

You may qualify if:

• Patients aged at least 18 years old and benefiting from a social security scheme
• Native French-speaking patients
• Patients treated for cancer of the oral cavity or oropharynx (surgical and / or radiotherapy and / or chemotherapy treatment)
• Patients in clinical remission for at least 6 months (chronic nature and stability of the disorders)
• All tumor sizes according to the tumor (T), node (N), and metastasis (M) categories (TNM classification) (T1 to T4)
• Patients with a perceptible speech disorder in a conversational situation or not (to allow the determination of fine deficits)
• Patients who do not object to carrying out the research

You may not qualify if:

• Patients with an associated pathology potentially responsible for speech or fluency disorders (joint, speech and language disorders of developmental, organic or functional origin, voice disorders of organic or functional origin, stammering , stammering, fluency disturbances, speech disturbances of neurological origin)
• Patients reporting an auditory complaint and not having a hearing aid
• Inability to provide the person with enlightened information and to ensure the subject's compliance because of impaired physical and / or psychological health,

Sponsors & Collaborators

• University Hospital, Toulouse: lead
• Laboratoire parole et langage: collaborator
• Laboratoire Information Avignon université: collaborator
• IRIT - Institut de Recherche en Informatique de Toulouse: collaborator

Study Sites (3)

AP- H Marseille - Hôpital de la Conception

Marseille, France

RECRUITING

Institut universitaire du Cancer de Toulouse - Oncopole

Toulouse, France

NOT YET RECRUITING

University Hospital Toulouse

Toulouse, France

RECRUITING

Related Publications (3)

• Balaguer M, Farinas J, Fichaux-Bourin P, Puech M, Pinquier J, Woisard V. Validation of the French Versions of the Speech Handicap Index and the Phonation Handicap Index in Patients Treated for Cancer of the Oral Cavity or Oropharynx. Folia Phoniatr Logop. 2020;72(6):464-477. doi: 10.1159/000503448. Epub 2019 Nov 15.

  PMID: 31734664 BACKGROUND

• Balaguer M, Champenois M, Farinas J, Pinquier J, Woisard V. The (head and neck) carcinologic handicap index: validation of a modular type questionnaire and its ability to prioritise patients' needs. Eur Arch Otorhinolaryngol. 2021 Apr;278(4):1159-1169. doi: 10.1007/s00405-020-06201-6. Epub 2020 Jul 14.

  PMID: 32666294 BACKGROUND

• Lalain M, Ghio A, Giusti L, Robert D, Fredouille C, Woisard V. Design and Development of a Speech Intelligibility Test Based on Pseudowords in French: Why and How? J Speech Lang Hear Res. 2020 Jul 20;63(7):2070-2083. doi: 10.1044/2020_JSLHR-19-00088. Epub 2020 Jun 29.

  PMID: 32598209 BACKGROUND

MeSH Terms

Conditions

Speech Intelligibility

Condition Hierarchy (Ancestors)

Speech; Verbal Behavior; Communication; Behavior

Study Officials

• Clémence DEVOUCOUX

  University Hospital, Toulouse

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Clémence DEVOUCOUX

CONTACT

06.50.72.24.85; devoucoux.c@chu-toulouse.fr

Anaïs GALTIER

CONTACT

05. 67. 77. 18 .70; Galtier.a@chu-toulouse.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 2, 2021
• First Posted: February 8, 2021
• Study Start: October 22, 2021
• Primary Completion: October 22, 2024
• Study Completion: October 22, 2024
• Last Updated: July 24, 2023

Record last verified: 2023-07

Data Sharing

• IPD Sharing: Will not share

Locations

FR (3)