NCT04741685

Brief Summary

Observational cross-sectional multicenter study about effectiveness of two different sensor augmented-pumps with low glucose predictive function in Type 1 Diabetes Mellitus (T1DM) adult patients in routine clinical practice.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
23

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Feb 2021

Shorter than P25 for all trials

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 29, 2021

Completed
7 days until next milestone

First Posted

Study publicly available on registry

February 5, 2021

Completed
10 days until next milestone

Study Start

First participant enrolled

February 15, 2021

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2021

Completed
9 days until next milestone

Study Completion

Last participant's last visit for all outcomes

June 10, 2021

Completed
Last Updated

June 11, 2021

Status Verified

June 1, 2021

Enrollment Period

4 months

First QC Date

January 29, 2021

Last Update Submit

June 10, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • TIR

    time in range (TIR, 70-180 mg/dL, 3.9-10 mmol/L) of the interstitial glucose

    during the procedure

Secondary Outcomes (9)

  • TBR

    during the procedure

  • TAR

    during the procedure

  • HbA1C

    during the procedure

  • GMI

    during the procedure

  • MAGE

    during the procedure

  • +4 more secondary outcomes

Study Arms (1)

SAP with LGS

Type 1 diabetes adults patients treated with sensor-augmented insulin pump with low glucose predictive suspension function

Device: TTSX2Device: MM640G

Interventions

TTSX2DEVICE

Treatment with Tandem T Slim X2 with Basal IQ

SAP with LGS
MM640GDEVICE

Treatment with Medtronic Minimed 640G with Smartguard

SAP with LGS

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Type 1 diabetes adult patients treated with sensor-augmented pump (TTSX2 or MM640G)

You may qualify if:

  • Type 1 diabetes
  • Treated with TTSX2 or MM640.

You may not qualify if:

  • Other kind of diabetes.
  • Serious mental disease.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Nuestra Señora de la Candelaria University Hospital

Santa Cruz de Tenerife, Santa Cruz De Tenerife, 38010, Spain

Location

Badajoz University Hospital

Badajoz, 06080, Spain

Location

Obispo Rafael Torija, St.

Ciudad Real, 13005, Spain

Location

Related Publications (1)

  • Moreno-Fernandez J, Beato-Vibora P, Olvera P, Garcia-Seco JA, Gallego-Gamero F, Herrera MT, Munoz-Rodriguez JR. Real-world outcomes of two different sensor-augmented insulin pumps with predictive low glucose suspend function in type 1 diabetes patients. Diabetes Res Clin Pract. 2021 Nov;181:109093. doi: 10.1016/j.diabres.2021.109093. Epub 2021 Oct 13.

MeSH Terms

Conditions

Diabetes Mellitus, Type 1

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAutoimmune DiseasesImmune System Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Target Duration
3 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

January 29, 2021

First Posted

February 5, 2021

Study Start

February 15, 2021

Primary Completion

June 1, 2021

Study Completion

June 10, 2021

Last Updated

June 11, 2021

Record last verified: 2021-06

Locations