NCT04737863

Brief Summary

The study compares the prognosis of cases treated with "selective root retreatment" to the cases treated with traditional retreatment approach

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2020

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2020

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

January 30, 2021

Completed
5 days until next milestone

First Posted

Study publicly available on registry

February 4, 2021

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 12, 2021

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2021

Completed
Last Updated

July 27, 2021

Status Verified

July 1, 2021

Enrollment Period

1.2 years

First QC Date

January 30, 2021

Last Update Submit

July 24, 2021

Conditions

Teeth, Endodontically-Treated

Outcome Measures

Primary Outcomes (1)

  • volumetric change of periapical lesion size in CBCT

    assessment of healing of periradicular infection in terms of change of the size of periapical lesion in CBCT analysis

    one year

Study Arms (2)

selective root canal retreatment

EXPERIMENTAL

retreatment process is performed to the affected root only

Procedure: Endodontic retreatment

traditional root canal retreatment

ACTIVE COMPARATOR

retreatment process is performed to all roots

Procedure: Endodontic retreatment

Interventions

Endodontic retreatmentPROCEDURE

Root canal retreatment in cases with secondary root canal infection

selective root canal retreatmenttraditional root canal retreatment

Eligibility Criteria

Age20 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • endodontically treated teeth
  • multirooted teeth
  • radiographic evidence of periradicular infection related to one root

You may not qualify if:

  • medically compromised patients
  • fused roots
  • root resorption
  • root fracture

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Dentistry, Ainshams University

Cairo, Egypt

Location

Related Publications (2)

  • Nudera WJ. Selective Root Retreatment: A Novel Approach. J Endod. 2015 Aug;41(8):1382-8. doi: 10.1016/j.joen.2015.02.035. Epub 2015 Apr 21.

    PMID: 25906919RESULT

  • Liang YH, Li G, Wesselink PR, Wu MK. Endodontic outcome predictors identified with periapical radiographs and cone-beam computed tomography scans. J Endod. 2011 Mar;37(3):326-31. doi: 10.1016/j.joen.2010.11.032.

    PMID: 21329816RESULT

MeSH Terms

Conditions

Tooth, Nonvital

Condition Hierarchy (Ancestors)

Dental Pulp DiseasesTooth DiseasesStomatognathic Diseases

Study Officials

  • Mohamed M Nagy, PhD

    Associate professor of Endodontics, Ain Shams University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

January 30, 2021

First Posted

February 4, 2021

Study Start

January 1, 2020

Primary Completion

March 12, 2021

Study Completion

April 30, 2021

Last Updated

July 27, 2021

Record last verified: 2021-07

Data Sharing

IPD Sharing
Will not share

Locations

EG(1)