Radiographic Characteristics of Mediastinal and Hilar Lymph Nodes in Sarcoidosis

NCT04735302 | Completed

• 1 other identifier: 24237859-153
• Study Type: observational
• Target: 192
• Locations: 1 country
• Sites: 1

Brief Summary

Background: This study aimed to investigate the diagnostic value of thoracic computerized tomography (CT) which is a noninvasive method making the diagnosis of sarcoidosis. Material-Method: The data of 816 patients who received endobronchial ultrasonography (EBUS) for mediastinal lymph node sampling and were subjected to other methods were retrospectively analyzed. 192 patients (sarcoidosis: 62, non-sarcoidosis) were included in the study. The thoracic CT findings of the patients were compared in terms of mediastinal lymph node and pulmonary parenchymal involvement.

Conditions

Sarcoidosis; Lymph Node Disease

Keywords

sarcoidosis; lymh nodes; Thorax tomography

Outcome Measures

Primary Outcomes (1)

• Assesment of biopsy necessay

  Diagnosis of sarcoidosis without lymph node biopsy by Thorax computed tomography

  11.012019-22.01.2021

Study Arms (2)

Sarcoidosis, Nonsarcoidosis

Other: Radiographic Feature

Malign, benign

Other: Radiographic Feature

Interventions

Radiographic Feature OTHER

Radiographic rewiev

Malign, benign; Sarcoidosis, Nonsarcoidosis

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study was planned by retrospectively analyzing the data of patients who received EBUS for sampling mediastinal lymph nodes and were subjected to other diagnostic methods such as mediastinoscopy and thoracotomy in the case of non-diagnostic results of EBUS at the Department of Pulmonology at the Faculty of Medicine at KTÜ between 1 January 2013 and 1 July 2019

You may qualify if:

• \- The patients who received EBUS for sampling mediastinal lymph nodes and were subjected to other diagnostic methods such as mediastinoscopy and thoracotomy in the case of non-diagnostic results of EBUS at the Department of Pulmonology at the Faculty of Medicine at KTÜ

You may not qualify if:

• The patients whose computerized thoracic tomography images at first admission were not available in the archives of our hospital were excluded

Sponsors & Collaborators

• Karadeniz Technical University: lead

Study Sites (1)

Department Of Chest Diseases, School Of medicine, Karadeniz Technical University

Trabzon, 61080, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Sarcoidosis

Condition Hierarchy (Ancestors)

Lymphoproliferative Disorders; Lymphatic Diseases; Hemic and Lymphatic Diseases; Hypersensitivity, Delayed; Hypersensitivity; Immune System Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor

Study Record Dates

• First Submitted: January 22, 2021
• First Posted: February 3, 2021
• Study Start: February 11, 2019
• Primary Completion: August 1, 2019
• Study Completion: January 22, 2021
• Last Updated: February 3, 2021

Record last verified: 2021-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)