NCT04730011

Brief Summary

Obsessive-compulsive disorders are very damaging illnesses; they can already appear in childhood and adolescence and become extremely chronic. With an average prevalence from 1-3%, they are among the most common psychiatric disorders in children and adolescents. 40% of diagnosed children and young adults display persistent and increasingly chronic symptoms and O-C disorders are highly complex syndromes with broadly varying manifestations. They arise from obsessive thoughts (ideas/thoughts or impulses, often senseless or tortured, that impose themselves or intrude) and obsessive behavior (ritualized patterns that must be frequently repeated).

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
32mo left

Started Jan 2021

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress67%
Jan 2021Dec 2028

Study Start

First participant enrolled

January 1, 2021

Completed
24 days until next milestone

First Submitted

Initial submission to the registry

January 25, 2021

Completed
4 days until next milestone

First Posted

Study publicly available on registry

January 29, 2021

Completed
7.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2028

Last Updated

May 13, 2025

Status Verified

May 1, 2025

Enrollment Period

8 years

First QC Date

January 25, 2021

Last Update Submit

May 12, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Symptoms severity of obsessive and compulsive symptoms in children and adolescents

    The clinician-report questionnaire (BY-BOCS) contains 19 items designed to assess severity of obsessive and compulsive symptoms in children and adolescents.The test uses a 4-point scale to rate the severity of their obsessive compulsive behaviors. Higher score means a worse outcome.

    12 months

Study Arms (1)

Treatment Group

EXPERIMENTAL

Patients are treated based on the Cognitive Behavioral Psychotherapy. This includes individual and group sessions over one week.

Behavioral: Short and Intensive Treatment

Interventions

Intensive Treatment Week with behavioural psychotherapy

Treatment Group

Eligibility Criteria

Age8 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Obsessive-Compulsive Disorder diagnosis
  • Male and female patients from 8-18 years
  • Good German language speaking skills
  • IQ of at least 75
  • At least four days' participation in the treatment/therapy week
  • Written agreement after clear explanation

You may not qualify if:

  • \- No complete participation in the intensive week treatment/therapy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Psychiatric University Clinics, Department of Child and Adolescent Psychiatry

Zurich, Canton of Zurich, 8032, Switzerland

RECRUITING

MeSH Terms

Conditions

Obsessive-Compulsive Disorder

Condition Hierarchy (Ancestors)

Anxiety DisordersMental Disorders

Study Officials

  • Susanne Walitza, Prof. Dr. med. Dipl.-Psych.

    Sponsor GmbH

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Susanne Walitza, Prof. Dr. med. Dipl.-Psych.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Head of the Department of Child and Adolescent Psychiatry

Study Record Dates

First Submitted

January 25, 2021

First Posted

January 29, 2021

Study Start

January 1, 2021

Primary Completion (Estimated)

December 31, 2028

Study Completion (Estimated)

December 31, 2028

Last Updated

May 13, 2025

Record last verified: 2025-05

Data Sharing

IPD Sharing
Will not share

Locations