Effectiveness of Cat-Cow Yoga in Managing Chronic Low Back Pain

NCT04723225 | Completed

• 1 other identifier: PPL-CAT2020
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

A randomized control trial is planned to investigate the effectiveness of Cat-Cow yoga as a treatment for chronic low back pain CLBP. An 12 weeks course of intervention will be provided to the candidates that will meet the eligibility criteria of the study. Substance P, beta endorphins and cortisol will be tested both the groups' pre and post treatment and then the difference from the baseline value will be determined.

Conditions

Chronic Low-back Pain

Keywords

Cat Cow Yoga; Yoga Therapy; Healthcare Providers; Substance P; Chronic low back pain; Cortisol; Beta Endorphins

Outcome Measures

Primary Outcomes (2)

• Pain Score

  It will assessed with the help of Numeric Pain Rating Scale. using a 0-10 scale, where 0 corresponds to "no pain" and 10 to "the greatest pain possible."

  3 Months

• Extent of Disability

  It will be detected with the help of Oswestry Low Back Pain Disability Questionnaire. This index is considered a standard to assess low back functionality, it has a total of 10 sections, and for each section with a possible score 5. The percentage improvement is calculated through the total possible score x 100.

  3 Months

Secondary Outcomes (5)

• Substance P

  3 Months

• Beta Endorphins

  3 Months

• Stress Score

  3 Months

• Cortisol

  3 Months

• Quality of Life Score

  3 Months

Study Arms (2)

Experimental

EXPERIMENTAL

Cat-Cow is one of the essential postures in yoga for its beneficial reasons. It is an alternate shift of posture from flexion of the back (rounded) to the extension of the back (arched). During each set of movement, inhalation and exhalation will be guided.

Other: Cat-Cow Yoga

Control

NO INTERVENTION

In control intervention group usual care will be provided.

Interventions

Cat-Cow Yoga OTHER

Cat-Cow is one of the essential postures in yoga for its beneficial reasons. It is an alternate shift of posture from flexion of the back (rounded) to the extension of the back (arched). During each set of movement, inhalation and exhalation will be guided

Experimental

Eligibility Criteria

• Age: 25 Years - 45 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Answer Yes to the following questions.
• Have low back pain constantly or on most days for the last three months.
• Have you seek care from health care provider due to back pain
• Average pain intensity, assessed using the Numerical Pain Rating (NPR) scale over the past week ≥ 2 on a 0-10 numerical pain scale.
• Roland Morris Disability Questionnaire score ≥ 4.
• Fear Avoidance Beliefs Questionnaire (FABQ) work subscale score \<19.

You may not qualify if:

• To be eligible for the study participants must not:
• Have a personal history of the following neurological disorders: Alzheimer's, Amyotrophic Lateral Sclerosis, Multiple Sclerosis, Parkinson's, Stroke
• Have a personal history of the following cardiorespiratory disorders: Congestive heart failure, Heart attack in past 24 months
• Have a personal history of the following musculoskeletal disorders: Rheumatoid Arthritis, pathologic fractures of the spine, avascular necrosis or osteonecrosis, severe osteoarthritis. Including a history of spine surgery or a hip arthroplasty
• Have active cancer
• Be Blind
• Report being pregnant, lactating, or that they anticipate becoming pregnant in the next 3-months
• Have a body mass index greater than 35 kg/m2
• Have clinical depression (i.e., subjects who score 24 or higher on the Center for Epidemiology Depression Scale).
• Have used narcotics or muscle relaxants within 30 days prior to study enrollment.

Sponsors & Collaborators

• University of Karachi: lead

Study Sites (1)

Koohi Goth Women Hospital

Karachi, Sindh, 24740, Pakistan

Location

Related Publications (13)

• Noushad S, Ansari B, Ahmed S. Effect of nature-based physical activity on post-traumatic growth among healthcare providers with post-traumatic stress. Stress Health. 2022 Oct;38(4):813-826. doi: 10.1002/smi.3135. Epub 2022 Feb 26.

  PMID: 35191173 BACKGROUND

• Noushad S, Ahmed S, Ansari B, Mustafa UH, Saleem Y, Hazrat H. Physiological biomarkers of chronic stress: A systematic review. Int J Health Sci (Qassim). 2021 Sep-Oct;15(5):46-59.

  PMID: 34548863 BACKGROUND

• Holtzman S, Beggs RT. Yoga for chronic low back pain: a meta-analysis of randomized controlled trials. Pain Res Manag. 2013 Sep-Oct;18(5):267-72. doi: 10.1155/2013/105919. Epub 2013 Jul 26.

  PMID: 23894731 RESULT

• Cramer H, Lauche R, Haller H, Dobos G. A systematic review and meta-analysis of yoga for low back pain. Clin J Pain. 2013 May;29(5):450-60. doi: 10.1097/AJP.0b013e31825e1492.

  PMID: 23246998 RESULT

• Goode AP, Coeytaux RR, McDuffie J, Duan-Porter W, Sharma P, Mennella H, Nagi A, Williams JW Jr. An evidence map of yoga for low back pain. Complement Ther Med. 2016 Apr;25:170-7. doi: 10.1016/j.ctim.2016.02.016. Epub 2016 Mar 3.

  PMID: 27062965 RESULT

• Zhu F, Zhang M, Wang D, Hong Q, Zeng C, Chen W. Yoga compared to non-exercise or physical therapy exercise on pain, disability, and quality of life for patients with chronic low back pain: A systematic review and meta-analysis of randomized controlled trials. PLoS One. 2020 Sep 1;15(9):e0238544. doi: 10.1371/journal.pone.0238544. eCollection 2020.

  PMID: 32870936 RESULT

• Alleva J, Hudgins T, Belous J, Kristin Origenes A. Chronic low back pain. Dis Mon. 2016 Sep;62(9):330-3. doi: 10.1016/j.disamonth.2016.05.012. Epub 2016 Jun 22. No abstract available.

  PMID: 27344193 RESULT

• Sanzarello I, Merlini L, Rosa MA, Perrone M, Frugiuele J, Borghi R, Faldini C. Central sensitization in chronic low back pain: A narrative review. J Back Musculoskelet Rehabil. 2016 Nov 21;29(4):625-633. doi: 10.3233/BMR-160685.

  PMID: 27062464 RESULT

• Patrick N, Emanski E, Knaub MA. Acute and chronic low back pain. Med Clin North Am. 2014 Jul;98(4):777-89, xii. doi: 10.1016/j.mcna.2014.03.005.

  PMID: 24994051 RESULT

• Zieglgansberger W. Substance P and pain chronicity. Cell Tissue Res. 2019 Jan;375(1):227-241. doi: 10.1007/s00441-018-2922-y. Epub 2018 Oct 3.

  PMID: 30284083 RESULT

• Kallman TF, Ghafouri B, Backryd E. Salivary beta-endorphin and substance P are not biomarkers of neuropathic chronic pain propensity. Heliyon. 2018 Aug 3;4(8):e00718. doi: 10.1016/j.heliyon.2018.e00718. eCollection 2018 Aug.

  PMID: 30116793 RESULT

• Lisowska B, Lisowski A, Siewruk K. Substance P and Chronic Pain in Patients with Chronic Inflammation of Connective Tissue. PLoS One. 2015 Oct 7;10(10):e0139206. doi: 10.1371/journal.pone.0139206. eCollection 2015.

  PMID: 26444559 RESULT

• Veening JG, Barendregt HP. The effects of beta-endorphin: state change modification. Fluids Barriers CNS. 2015 Jan 29;12:3. doi: 10.1186/2045-8118-12-3.

  PMID: 25879522 RESULT

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: January 20, 2021
• First Posted: January 25, 2021
• Study Start: January 30, 2021
• Primary Completion: December 15, 2022
• Study Completion: January 20, 2023
• Last Updated: February 8, 2023

Record last verified: 2023-02

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)