NCT04722744

Brief Summary

compare CAD/CAM implant supported screw-retained metal frameworks based on actual versus screw-mented ones based on virtual implant position regarding marginal bone changes.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2022

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 20, 2021

Completed
5 days until next milestone

First Posted

Study publicly available on registry

January 25, 2021

Completed
1.1 years until next milestone

Study Start

First participant enrolled

March 1, 2022

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2023

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2023

Completed
Last Updated

March 25, 2022

Status Verified

March 1, 2022

Enrollment Period

1.2 years

First QC Date

January 20, 2021

Last Update Submit

March 11, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • marginal bone changes.

    Using long cone paralleling technique , RINN XCP and Digora (digital periapical radiographs for standardization. the bone loss is measured in mm

    6 months

Secondary Outcomes (1)

  • Patient satisfaction

    6 months

Study Arms (2)

screwmented metal frameworks based on virtual implant position.

EXPERIMENTAL

this group will receive a CAD CAM restoration based on virtually planned implant position.

Procedure: screwmented metal frameworks

screw-retained metal frameworks based on actual implant position.

ACTIVE COMPARATOR

this group will receive screw retained CAD CAM restoration based on actual implant position using conventional open tray impression.

Procedure: screwmented metal frameworks

Interventions

Intervention group: in which the edentulous area will be restored with 3-implant, screwmented CAD/CAM frameworks constructed based on planned implant positions

screw-retained metal frameworks based on actual implant position.screwmented metal frameworks based on virtual implant position.

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Kennedy class I, II Or IV cases.
  • Opposing completely dentulous, fully or partially restored dentition.
  • Good oral hygiene.
  • The patient should have bone for implants, minimum bone height 10 mm and minimum bone diameter should be 6 mm.
  • Adequate inter arch space for restoration 15mm or more.
  • Adult patients age ≥18 years

You may not qualify if:

  • any medical disorder that could complicate surgical phase or affect osteointegration. Radiation chemotherapy.
  • smokers more than 10/daily.
  • Uncooperative patients.
  • Patients with Para-functional habits
  • Patients with severe periodontal diseases.
  • Patients with limited mouth opening.
  • Presence of intraoral pathological lesions.
  • Diabetic (HbA1c \>7.5%).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Dentistry

Cairo, Manial, 11555, Egypt

RECRUITING

MeSH Terms

Conditions

Patient SatisfactionBone Diseases, Metabolic

Condition Hierarchy (Ancestors)

Treatment Adherence and ComplianceHealth BehaviorBehaviorBone DiseasesMusculoskeletal DiseasesMetabolic DiseasesNutritional and Metabolic Diseases

Study Officials

  • Azza Hussein, PhD

    Professor of Prosthodontics

    STUDY CHAIR
  • Mohamed ElKhashab, PhD

    Lecturer of prosthodontics

    STUDY DIRECTOR
  • Iman Radi, PhD

    Professor of Prosthodontics

    STUDY DIRECTOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
assistant lecturer

Study Record Dates

First Submitted

January 20, 2021

First Posted

January 25, 2021

Study Start

March 1, 2022

Primary Completion

May 1, 2023

Study Completion

June 1, 2023

Last Updated

March 25, 2022

Record last verified: 2022-03

Locations