The Electrophysiological Signature of the Mental Fatigue-induced Impairment in Endurance Performance
1 other identifier
interventional
25
1 country
1
Brief Summary
The purpose of this project is to provide further insights into the neurophysiology behind the MF-induced impairment in endurance performance. The aim is to perform a randomized controlled trial in which we partly replicate studies of Marcora et al. (2009) and Bigliassi et al. (2017), while extensively monitoring brain activity during the entire protocol (i.e. both cognitive and physical tasks) by using EEG.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Feb 2021
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 22, 2020
CompletedFirst Posted
Study publicly available on registry
January 22, 2021
CompletedStudy Start
First participant enrolled
February 1, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 30, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
July 31, 2021
CompletedJanuary 22, 2021
January 1, 2021
5 months
September 22, 2020
January 19, 2021
Conditions
Outcome Measures
Primary Outcomes (5)
Electroencephalogram data
During whole of the trials EEG data will be gathered, each trial will last one and a half to two hours. EEG power in delta, theta, alpha, beta band.
1 hours 30 minutes - 2 hours
Reaction Time Flanker Task
Reaction Time will be assessed during Flanker task
Total of 10 minutes
Accuracy Flanker Task
Accuracy will be assessed during Flanker task
Total of 10 minutes
Reaction Time Stroop Task
Reaction Time will be assessed during Stroop task
60 minutes
Accuracy performance Stroop Task
Accuracy will be assessed during Stroop task
60 minutes
Study Arms (4)
Mental Fatigue (Stroop) - Chair task
EXPERIMENTALParticipants will be performing the Chair Task (150 submaximal dynamic knee extensions at 50% of their maximal voluntary contraction (MVC)) when mentally fatigued. A 60 minute variant of the Stroop task will be used to induce the mental fatigue. During the whole trial EEG will be measured.
Control Task (Documentary) - Chair Task
PLACEBO COMPARATORIn the control task subjects will have to watch a documentary on the same computer screen as that used for the experimental trial. These documentaries are chosen based on their emotionally neutral, yet engaging content. This will be followed by the Chair Task, During the whole trial EEG will be measured.
Mental Fatigue (Stroop) - Bike Task
EXPERIMENTALParticipants will be performing the Bike Task (a 9 min cycling task performed at 45 rpm with intensity being constant and will be 10% below VT) when mentally fatigued. A 60 minute variant of the Stroop task will be used to induce the mental fatigue. During the whole trial EEG will be measured.
Control task (Documentary) - Bike Task
PLACEBO COMPARATORIn the control task subjects will have to watch a documentary on the same computer screen as that used for the experimental trial. These documentaries are chosen based on their emotionally neutral, yet engaging content. This will be followed by the Bike Task, During the whole trial EEG will be measured.
Interventions
A modified Stroop task of approximately 60 min will be used in order to induce mental fatigue (MF). This will be based on their performance during the max test that was conducted during the familiarization session. In this task, which will be partitioned in 4 blocks of 468 stimuli, four colored words ("rood", "blauw", "groen" and "geel") will be presented one at a time on a computer screen. The participants will be required to indicate the color of the word, ignoring the meaning of the word itself.
In the control task subjects will have to watch a documentary of 60 min on the same computer screen as the one used for the experimental trial. In order to avoid under- and over-arousal the subjects will have the opportunity to choose between several documentaries as proposed by the research team. During the control task physiological and psychological measures will be assessed at the same time points as during the mental fatigue trial.
Eligibility Criteria
You may qualify if:
- Healthy (No neurological or cardiovascular disorders)
- Male or female
- No medication
- Non-smoker
- Between 18 and 35 years old
- Recreational athlete population (performance level 2 or 3 for men according to De Pauw et al. (2013) and performance level 2 or 3 for woman according to Decroix et al. (2016)
You may not qualify if:
- Injuries over the last 6 months
- Suffering from any cardiovascular condition
- Use of medication
- Suffering from other health conditions at the time of testing
- Use of caffeine or alcohol 24 hours prior to each trial
- Heavy efforts 24 hours prior to each trial
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Human Physiology and Sports Physiotherapy Research Group
Brussels, Elsene, 1050, Belgium
Related Publications (1)
Proost M, Habay J, DE Wachter J, DE Pauw K, Marusic U, Meeusen R, DE Bock S, Roelands B, VAN Cutsem J. The Impact of Mental Fatigue on a Strength Endurance Task: Is There a Role for the Movement-Related Cortical Potential? Med Sci Sports Exerc. 2024 Mar 1;56(3):435-445. doi: 10.1249/MSS.0000000000003322. Epub 2023 Oct 16.
PMID: 37847068DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Purpose
- BASIC SCIENCE
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
September 22, 2020
First Posted
January 22, 2021
Study Start
February 1, 2021
Primary Completion
June 30, 2021
Study Completion
July 31, 2021
Last Updated
January 22, 2021
Record last verified: 2021-01
Data Sharing
- IPD Sharing
- Will not share