NCT04719325

Brief Summary

14 patients having recent anterior mandibular fracture divided into two groups. Group A has 6 patients and treated using Herbert bone screw, and group B has 6 patients and treated using lag screw. Clinical follow-up was conducted after 24-hours, one, four, six, and twelve weeks. In addition, a radiographic investigation was performed after twelve weeks to estimate the mean bone density across the fracture line.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 18, 2019

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 15, 2020

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 15, 2020

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

January 17, 2021

Completed
5 days until next milestone

First Posted

Study publicly available on registry

January 22, 2021

Completed
Last Updated

January 22, 2021

Status Verified

January 1, 2021

Enrollment Period

6 months

First QC Date

January 17, 2021

Last Update Submit

January 20, 2021

Conditions

Outcome Measures

Primary Outcomes (3)

  • Change in bone density

    By using digital orthopantomogram bone density was evaluated

    baseline and 3 months

  • change in pain scores

    assessed through a 10-point Visual Analogue Scale (VAS). (0-1= None, 2-4= Mild, 5-7= Moderate, 8-10= Severe)

    24 hours, 1 week , 4 Weeks and 6 weeks

  • presence of Intra-fragmentary mobility

    assessed by bi-manual palpation across the fracture site

    24 hours

Study Arms (2)

Herbert screw

EXPERIMENTAL
Other: Herbert screw

Lag screw

ACTIVE COMPARATOR
Other: Lag screw

Interventions

Fracture line exposed through intra-oral approach. bone reduction into proper anatomical occlusion and application of Herbert screw

Herbert screw

Fracture line exposed through intra-oral approach. bone reduction into proper anatomical occlusion. Application of either lag screw according to Champy's osteosynthesis lines.

Lag screw

Eligibility Criteria

Age20 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients suffering from recent, uninfected anterior mandibular fracture.
  • Adult patients from 20-60 years old with no gender predilection agreed to present for follow-up visits for a minimum postoperative period of 3 months.
  • Fracture that demands open reduction and internal fixation.

You may not qualify if:

  • Medically compromised patients contradicting operations.
  • Existence of infection at the fracture line.
  • Pathological fracture.
  • An old fracture.
  • Completely edentulous patient

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University, Egypt

Alexandria, Azarita, 00203, Egypt

Location

MeSH Terms

Conditions

Mandibular Fractures

Condition Hierarchy (Ancestors)

Jaw FracturesMaxillofacial InjuriesFacial InjuriesCraniocerebral TraumaTrauma, Nervous SystemNervous System DiseasesSkull FracturesFractures, BoneWounds and Injuries

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Assistant lecturer of DPH and Clinical statistician

Study Record Dates

First Submitted

January 17, 2021

First Posted

January 22, 2021

Study Start

October 18, 2019

Primary Completion

April 15, 2020

Study Completion

June 15, 2020

Last Updated

January 22, 2021

Record last verified: 2021-01

Locations