Trials Sponsors Conditions Drugs Pricing

Conditions

Functional Gastrointestinal Disorders Overlap Syndromes

Keywords

functional gastrointestinal disorderoverlap syndromesfunctional dyspepsiairritable bowel syndromenon-erosive reflux diseasereflux hypersensitivity

Outcome Measures

Primary Outcomes (3)

Symptom severity score (5 Likert scale, from 0 to 4)
FGID symptom severity score score by K-BDQ
per 16 years
Hospital anxiety and depression scale (HADS)
by HADS questionnaire
per 16 years
Genetic polymorphisms of SLC6A4 5-HTTLPR, GNB3, ADRA2, TNFA, IL10 gene
per 16 years

Secondary Outcomes (1)

Prevalence of overlap syndromes among FGIDs(NERD or RH, FD, and IBS) patients
per 16 years

Study Arms (2)

FGIDs

Patient who were diagnosed with NERD/RH, FD, IBS and their overlaps (NERD/RH-FD, NERD/RH-IBS, FD-IBS, NERD/RH-FD-IBS)

Healthy controls

Subjects who underwent GI evaluations as part of health check-up or for other problems, such as mild abdominal discomfort or pain for a relatively short period of time, but had no organic problems during GI endoscopy

Eligibility Criteria

Age18 Years - 80 Years

Sexall

Healthy VolunteersYes

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Patient who were diagnosed with NERD/RH, FD, IBS and their overlaps (NERD/RH-FD, NERD/RH-IBS, FD-IBS, NERD/RH-FD-IBS) and healthy controls.

You may qualify if:

FGID group

Sponsors & Collaborators

Seoul National University Bundang Hospital
Otherlead

MeSH Terms

Conditions

Gastrointestinal DiseasesIrritable Bowel SyndromeNon-Erosive Reflux Disease

Condition Hierarchy (Ancestors)

Digestive System DiseasesColonic Diseases, FunctionalColonic DiseasesIntestinal DiseasesGastroesophageal RefluxEsophageal Motility DisordersDeglutition DisordersEsophageal Diseases

Study Officials

Nayoung Kim, Professor
Seoul National University Bundang Hospital
PRINCIPAL INVESTIGATOR

Enrollment

800 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: CASE CONTROL
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Professor

Study Record Dates

First Submitted

January 10, 2021

First Posted

January 15, 2021

Study Start

July 2004

Actual (reported)

Overlap FGIDs and Genetic Polymorphism

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (3)

Secondary Outcomes (1)

Study Arms (2)

FGIDs

Healthy controls

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (3)

Secondary Outcomes (1)

Study Arms (2)

FGIDs

Healthy controls

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record