NCT04709991

Brief Summary

To demonstrate that the use of EndoNaut for endovascular procedures on the femoropopliteal axis has a clinical impact for the patient (decrease in irradiation and the volume of contrast product) as well as for nursing staff (reduction in irradiation) compared to procedures performed without EndoNaut.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2019

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2019

Completed
2 years until next milestone

First Submitted

Initial submission to the registry

January 12, 2021

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 14, 2021

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2021

Completed
Last Updated

October 6, 2021

Status Verified

October 1, 2021

Enrollment Period

2.5 years

First QC Date

January 12, 2021

Last Update Submit

October 5, 2021

Conditions

Outcome Measures

Primary Outcomes (4)

  • Volume of contrast product used during the routine care procedure (ml)

    Volume are reported in mL

    1 day At enrollment

  • Irradiation parameters: evaluation of the Fluoroscopy duration (min)

    Parameter given by the X-ray imaging device

    1 day At enrollment

  • Irradiation parameters: dose-area quantification (mGy/m2)

    Parameter given by the X-ray imaging device

    1 day At enrollment

  • Irradiation parameters: measurement of air Kerma (mGy)

    Parameter given by the X-ray imaging device

    1 day At enrollment

Study Arms (2)

Procedures with EndoNaut

Procedure: Endovascular procedure

Procedures without Endonaut

Procedure: Endovascular procedure

Interventions

Creation of a bone and arterial panorama using EndoNaut® software. The routine care procedure begins with staged injections of contrast medium to provide a map of the lesions. The lesions are then treated by angioplasty with or without stenting.

Procedures with EndoNautProcedures without Endonaut

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with chronic occlusive arthritis of the Lower Limbs with lesions on the femoro-popliteal stage and candidates for endovascular treatment of these lesions.

You may qualify if:

  • Patients with peripheral arterial disease of the lower limbs, all clinical stages, lesions of the femoro-popliteal stage and candidates for endovascular treatment of these lesions.
  • Major patients
  • Patients not opposed to their participation in the study

You may not qualify if:

  • \- Patients requiring conventional surgical revascularization.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CH Libourne

Libourne, France

Location

Related Publications (1)

  • Caradu C, Stenson K, Houmaida H, Le Ny J, Lalys F, Ducasse E, Gheysens B. EndoNaut two-dimensional fusion imaging with a mobile C-arm for endovascular treatment of occlusive peripheral arterial disease. J Vasc Surg. 2022 Feb;75(2):651-659.e1. doi: 10.1016/j.jvs.2021.08.069. Epub 2021 Sep 10.

MeSH Terms

Conditions

Peripheral Arterial Disease

Interventions

Endovascular Procedures

Condition Hierarchy (Ancestors)

AtherosclerosisArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCardiovascular DiseasesPeripheral Vascular Diseases

Intervention Hierarchy (Ancestors)

Vascular Surgical ProceduresCardiovascular Surgical ProceduresSurgical Procedures, OperativeMinimally Invasive Surgical Procedures

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 12, 2021

First Posted

January 14, 2021

Study Start

January 1, 2019

Primary Completion

July 1, 2021

Study Completion

July 1, 2021

Last Updated

October 6, 2021

Record last verified: 2021-10

Data Sharing

IPD Sharing
Will not share

Locations