Effect of High Frequency Transcranial Magnetic Stimulation on Recovery of Chronic Post-Stroke Aphasia
Role of rTMS in Recovery of Chronic Post Stroke Aphasia
1 other identifier
interventional
20
1 country
1
Brief Summary
high frequency excitatory rTMS applied over the dominant hemisphere in chronic post stroke aphasic patients to help the restoration of function by the left hemisphere
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jun 2020
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2020
CompletedFirst Submitted
Initial submission to the registry
January 9, 2021
CompletedFirst Posted
Study publicly available on registry
January 13, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2021
CompletedAugust 6, 2021
August 1, 2021
8 months
January 9, 2021
August 2, 2021
Conditions
Outcome Measures
Primary Outcomes (1)
evaluate the recovery of post stroke aphasia by non invasive procedure without language therapy
rTMs is non invasive procedure may help improvement of speech performance
1 month to assess the recovery
Study Arms (1)
aphasic patients
OTHERpost stroke aphasic patients will receive 10 sessions of high frequency rTMS 3 times per week over the damaged hemisphere without language therapy
Interventions
applying high frequency TMS over the damaged hemisphere in chronic post stroke aphasic patients
Eligibility Criteria
You may qualify if:
- chronic post stroke nonfluent aphasia due to first-ever ischemic stroke in the distribution of middle cerebral artery diagnosed clinically and documented by computed tomography or magnetic resonance imaging on the brain
- Right handedness
- Both sexe groups
- Age ranged from 33 to 66 years old,
- Duration is at least 4 months from stroke onset,
- patients never received speech therapy before
- Educated for at least 10 years of education.
You may not qualify if:
- Aphasia due to head injury or neurological disease other than stroke,
- unstable cardiac dysrhythmia or cardiac pacemaker
- unstable or critically ill patients
- current or history of epilepsy, skull wounds and pregnant females.
- patients with severe grade of weakness which interfere with writing ability.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
Study Sites (1)
Haidy Elshebawy
Cairo, 11931, Egypt
Related Publications (1)
Fahmy EM, Elshebawy HM. Effect of High Frequency Transcranial Magnetic Stimulation on Recovery of Chronic Post-Stroke Aphasia. J Stroke Cerebrovasc Dis. 2021 Aug;30(8):105855. doi: 10.1016/j.jstrokecerebrovasdis.2021.105855. Epub 2021 May 25.
PMID: 34049013DERIVED
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Haidy Elshebawy, lecturer
El kasr al ainy hospitals ,faculty of medicine ,cairo university
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- lecturer of Neurology ,MD ,faculty of medicine ,Cairo University
Study Record Dates
First Submitted
January 9, 2021
First Posted
January 13, 2021
Study Start
June 1, 2020
Primary Completion
February 1, 2021
Study Completion
May 1, 2021
Last Updated
August 6, 2021
Record last verified: 2021-08
Data Sharing
- IPD Sharing
- Will not share